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DTG + 3TC FDC — Competitive Intelligence Brief
phase 3
Antiretroviral combination (INSTI + NRTI)
HIV integrase (DTG); HIV reverse transcriptase (3TC)
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
DTG + 3TC FDC (DTG + 3TC FDC) — ViiV Healthcare. DTG (dolutegravir) inhibits HIV integrase to prevent viral replication, while 3TC (lamivudine) inhibits reverse transcriptase to block HIV from converting its RNA genome into DNA.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DTG + 3TC FDC TARGET | DTG + 3TC FDC | ViiV Healthcare | phase 3 | Antiretroviral combination (INSTI + NRTI) | HIV integrase (DTG); HIV reverse transcriptase (3TC) | |
| Switch to DTG + 3TC | Switch to DTG + 3TC | Hospitales Universitarios Virgen del Rocío | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir / Lamivudine Pill | Dolutegravir / Lamivudine Pill | Charlotte-Paige Rolle, MD | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine | Dolutegravir/Lamivudine | Saint Michael's Medical Center | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Raltegravir and truvada | Raltegravir and truvada | The University of Texas Health Science Center, Houston | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine as a single pill | Dolutegravir/Lamivudine as a single pill | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Raltegravir and Abacavir/Lamivudine | Raltegravir and Abacavir/Lamivudine | Denver Infectious Disease Consultants, PLLC | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase, HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination (INSTI + NRTI) class)
- ViiV Healthcare · 2 drugs in this class
- Denver Infectious Disease Consultants, PLLC · 1 drug in this class
- Fundacion SEIMC-GESIDA · 1 drug in this class
- Fundação Bahiana de Infectologia · 1 drug in this class
- Charlotte-Paige Rolle, MD · 1 drug in this class
- Saint Michael's Medical Center · 1 drug in this class
- The University of Texas Health Science Center, Houston · 1 drug in this class
- Hospitales Universitarios Virgen del Rocío · 1 drug in this class
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Cite this brief
Drug Landscape (2026). DTG + 3TC FDC — Competitive Intelligence Brief. https://druglandscape.com/ci/dtg-3tc-fdc. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing