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DTG + 3TC FDC — Competitive Intelligence Brief

DTG + 3TC FDC (DTG + 3TC FDC) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiretroviral combination (INSTI + NRTI). Area: Infectious Disease / Virology.

phase 3 Antiretroviral combination (INSTI + NRTI) HIV integrase (DTG); HIV reverse transcriptase (3TC) Infectious Disease / Virology Small molecule Live · refreshed every 30 min

Target snapshot

DTG + 3TC FDC (DTG + 3TC FDC) — ViiV Healthcare. DTG (dolutegravir) inhibits HIV integrase to prevent viral replication, while 3TC (lamivudine) inhibits reverse transcriptase to block HIV from converting its RNA genome into DNA.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DTG + 3TC FDC TARGET DTG + 3TC FDC ViiV Healthcare phase 3 Antiretroviral combination (INSTI + NRTI) HIV integrase (DTG); HIV reverse transcriptase (3TC)
Switch to DTG + 3TC Switch to DTG + 3TC Hospitales Universitarios Virgen del Rocío marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir / Lamivudine Pill Dolutegravir / Lamivudine Pill Charlotte-Paige Rolle, MD marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir/Lamivudine Dolutegravir/Lamivudine Saint Michael's Medical Center marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Raltegravir and truvada Raltegravir and truvada The University of Texas Health Science Center, Houston marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir/Lamivudine as a single pill Dolutegravir/Lamivudine as a single pill Fundacion SEIMC-GESIDA marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Raltegravir and Abacavir/Lamivudine Raltegravir and Abacavir/Lamivudine Denver Infectious Disease Consultants, PLLC marketed Antiretroviral combination (INSTI + NRTI) HIV integrase, HIV reverse transcriptase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiretroviral combination (INSTI + NRTI) class)

  1. ViiV Healthcare · 2 drugs in this class
  2. Denver Infectious Disease Consultants, PLLC · 1 drug in this class
  3. Fundacion SEIMC-GESIDA · 1 drug in this class
  4. Fundação Bahiana de Infectologia · 1 drug in this class
  5. Charlotte-Paige Rolle, MD · 1 drug in this class
  6. Saint Michael's Medical Center · 1 drug in this class
  7. The University of Texas Health Science Center, Houston · 1 drug in this class
  8. Hospitales Universitarios Virgen del Rocío · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DTG + 3TC FDC — Competitive Intelligence Brief. https://druglandscape.com/ci/dtg-3tc-fdc. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing