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DTG/3TC — Competitive Intelligence Brief
marketed
Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor)
HIV integrase; HIV reverse transcriptase
Infectious Disease (HIV/AIDS)
Small molecule
Live · refreshed every 30 min
Target snapshot
DTG/3TC (DTG/3TC) — University of Nairobi. DTG/3TC is a fixed-dose combination of dolutegravir (an integrase strand transfer inhibitor) and lamivudine (a nucleoside reverse transcriptase inhibitor) that blocks HIV replication by inhibiting two key viral enzymes.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DTG/3TC TARGET | DTG/3TC | University of Nairobi | marketed | Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor) | HIV integrase; HIV reverse transcriptase | |
| Switch to DTG + 3TC | Switch to DTG + 3TC | Hospitales Universitarios Virgen del Rocío | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Raltegravir and truvada | Raltegravir and truvada | The University of Texas Health Science Center, Houston | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine as a single pill | Dolutegravir/Lamivudine as a single pill | Fundacion SEIMC-GESIDA | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir/Lamivudine | Dolutegravir/Lamivudine | Saint Michael's Medical Center | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Dolutegravir / Lamivudine Pill | Dolutegravir / Lamivudine Pill | Charlotte-Paige Rolle, MD | marketed | Antiretroviral combination (INSTI + NRTI) | HIV integrase; HIV reverse transcriptase | |
| Raltegravir; Abacavir/Lamivudine | Raltegravir; Abacavir/Lamivudine | Central Institute of Epidemiology, Moscow, Russia | marketed | Antiretroviral combination therapy (integrase inhibitor + nucleoside reverse transcriptase inhibitors) | HIV integrase; HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor) class)
- University of Nairobi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). DTG/3TC — Competitive Intelligence Brief. https://druglandscape.com/ci/dtg-3tc. Accessed 2026-05-13.
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