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DTG/3TC — Competitive Intelligence Brief

DTG/3TC (DTG/3TC) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor). Area: Infectious Disease (HIV/AIDS).

marketed Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor) HIV integrase; HIV reverse transcriptase Infectious Disease (HIV/AIDS) Small molecule Live · refreshed every 30 min

Target snapshot

DTG/3TC (DTG/3TC) — University of Nairobi. DTG/3TC is a fixed-dose combination of dolutegravir (an integrase strand transfer inhibitor) and lamivudine (a nucleoside reverse transcriptase inhibitor) that blocks HIV replication by inhibiting two key viral enzymes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DTG/3TC TARGET DTG/3TC University of Nairobi marketed Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor) HIV integrase; HIV reverse transcriptase
Switch to DTG + 3TC Switch to DTG + 3TC Hospitales Universitarios Virgen del Rocío marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Raltegravir and truvada Raltegravir and truvada The University of Texas Health Science Center, Houston marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir/Lamivudine as a single pill Dolutegravir/Lamivudine as a single pill Fundacion SEIMC-GESIDA marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir/Lamivudine Dolutegravir/Lamivudine Saint Michael's Medical Center marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Dolutegravir / Lamivudine Pill Dolutegravir / Lamivudine Pill Charlotte-Paige Rolle, MD marketed Antiretroviral combination (INSTI + NRTI) HIV integrase; HIV reverse transcriptase
Raltegravir; Abacavir/Lamivudine Raltegravir; Abacavir/Lamivudine Central Institute of Epidemiology, Moscow, Russia marketed Antiretroviral combination therapy (integrase inhibitor + nucleoside reverse transcriptase inhibitors) HIV integrase; HIV reverse transcriptase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antiretroviral combination (integrase strand transfer inhibitor + nucleoside reverse transcriptase inhibitor) class)

  1. University of Nairobi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DTG/3TC — Competitive Intelligence Brief. https://druglandscape.com/ci/dtg-3tc. Accessed 2026-05-13.

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