Last reviewed · How we verify
Doxycycline and tauroursodeoxycholic acid — Competitive Intelligence Brief
phase 3
Combination therapy (antibiotic + bile acid derivative)
Matrix metalloproteinases, FXR (farnesoid X receptor), TGR5 (G-protein coupled bile acid receptor 1)
Hepatology / Gastroenterology
Small molecule
Live · refreshed every 30 min
Target snapshot
Doxycycline and tauroursodeoxycholic acid (Doxycycline and tauroursodeoxycholic acid) — Fondazione IRCCS Policlinico San Matteo di Pavia. Doxycycline and tauroursodeoxycholic acid combination works by reducing inflammation and oxidative stress while promoting bile acid signaling to protect mitochondrial function and reduce hepatocellular injury.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Doxycycline and tauroursodeoxycholic acid TARGET | Doxycycline and tauroursodeoxycholic acid | Fondazione IRCCS Policlinico San Matteo di Pavia | phase 3 | Combination therapy (antibiotic + bile acid derivative) | Matrix metalloproteinases, FXR (farnesoid X receptor), TGR5 (G-protein coupled bile acid receptor 1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination therapy (antibiotic + bile acid derivative) class)
- Fondazione IRCCS Policlinico San Matteo di Pavia · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Doxycycline and tauroursodeoxycholic acid — Competitive Intelligence Brief. https://druglandscape.com/ci/doxycycline-and-tauroursodeoxycholic-acid. Accessed 2026-05-16.
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