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Dose -mFOLFIRINOX — Competitive Intelligence Brief

Dose -mFOLFIRINOX (Dose -mFOLFIRINOX) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Combination chemotherapy regimen. Area: Oncology.

phase 3 Combination chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Dose -mFOLFIRINOX (Dose -mFOLFIRINOX) — Pancreatic Cancer Action Network. mFOLFIRINOX is a combination chemotherapy regimen that uses multiple cytotoxic agents to damage cancer cell DNA and inhibit cell division.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Dose -mFOLFIRINOX TARGET Dose -mFOLFIRINOX Pancreatic Cancer Action Network phase 3 Combination chemotherapy regimen
Dexamethasona, Idarubicine, ARA-C, Methotrexate Dexamethasona, Idarubicine, ARA-C, Methotrexate PETHEMA Foundation marketed Combination chemotherapy regimen
PTH followed by dose dense AC of FEC PTH followed by dose dense AC of FEC Agendia marketed Combination chemotherapy regimen with monoclonal antibody HER2 receptor; microtubule; DNA (topoisomerase II)
Consolidation Chemotherapy Consolidation Chemotherapy National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos marketed Combination chemotherapy regimen
FEC FEC Hoffmann-La Roche marketed Combination chemotherapy regimen
chemotherapy of mFOLFOX6 or FOLFIRI chemotherapy of mFOLFOX6 or FOLFIRI Xu jianmin marketed Combination chemotherapy regimen Thymidylate synthase (5-FU), DNA topoisomerase I (irinotecan), DNA (oxaliplatin)
Carboplatin, Etoposide, Ifosfamide Carboplatin, Etoposide, Ifosfamide University Hospital Muenster marketed Combination chemotherapy regimen DNA (multiple mechanisms: alkylation, cross-linking, topoisomerase II inhibition)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Combination chemotherapy regimen class)

  1. Sun Yat-sen University · 5 drugs in this class
  2. Sixth Affiliated Hospital, Sun Yat-sen University · 2 drugs in this class
  3. Hoffmann-La Roche · 2 drugs in this class
  4. University Hospital, Bordeaux · 2 drugs in this class
  5. Beijing Friendship Hospital · 1 drug in this class
  6. Centre Hospitalier Universitaire Dijon · 1 drug in this class
  7. Amgen · 1 drug in this class
  8. Chungnam National University Hospital · 1 drug in this class
  9. AstraZeneca · 1 drug in this class
  10. Children's Cancer Group, China · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dose -mFOLFIRINOX — Competitive Intelligence Brief. https://druglandscape.com/ci/dose-mfolfirinox. Accessed 2026-05-14.

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