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Dose-matched Placebo to Suvorexant — Competitive Intelligence Brief

Dose-matched Placebo to Suvorexant (Dose-matched Placebo to Suvorexant) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Orexin receptor antagonist. Area: Neurology / Sleep Medicine.

phase 3 Orexin receptor antagonist OX1R and OX2R (orexin receptors) Neurology / Sleep Medicine Small molecule Live · refreshed every 30 min

Target snapshot

Dose-matched Placebo to Suvorexant (Dose-matched Placebo to Suvorexant) — Merck Sharp & Dohme LLC. This is a placebo control formulation matched to suvorexant, an orexin receptor antagonist used to promote sleep.

Comparator set (5 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Dose-matched Placebo to Suvorexant TARGET Dose-matched Placebo to Suvorexant Merck Sharp & Dohme LLC phase 3 Orexin receptor antagonist OX1R and OX2R (orexin receptors)
Quviviq DARIDOREXANT Idorsia marketed Orexin Receptor Antagonist [EPC] Orexin receptor type 1 2022-01-01
Dayvigo LEMBOREXANT Eisai marketed Orexin Receptor Antagonist [EPC] Orexin receptor type 2 2019-01-01
Suvorexant (Belsomra) Suvorexant (Belsomra) Massachusetts General Hospital marketed Orexin receptor antagonist Orexin receptor 1 (OX1R) and Orexin receptor 2 (OX2R)
Suvorexant Low Dose (LD) Suvorexant Low Dose (LD) Merck Sharp & Dohme LLC phase 3 Orexin receptor antagonist OX1R and OX2R (orexin receptors 1 and 2)
Suvorexant High Dose (HD) Suvorexant High Dose (HD) Merck Sharp & Dohme LLC phase 3 Orexin receptor antagonist OX1R and OX2R (orexin receptors 1 and 2)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Orexin receptor antagonist class)

  1. Merck Sharp & Dohme LLC · 3 drugs in this class
  2. Apnimed · 1 drug in this class
  3. Idorsia Pharmaceuticals Ltd. · 1 drug in this class
  4. Massachusetts General Hospital · 1 drug in this class
  5. Shanghai Mental Health Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dose-matched Placebo to Suvorexant — Competitive Intelligence Brief. https://druglandscape.com/ci/dose-matched-placebo-to-suvorexant. Accessed 2026-05-16.

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