Who are Dornase Alfa Inhalant Solution [Pulmozyme]'s main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): recAP, DNase, Pulmozyme®, rhDNAse, Dornase alfa (Pulmozyme), Fabrazyme (agalsidase beta).

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Last reviewed 2026-05-17 · How we verify

Dornase Alfa Inhalant Solution [Pulmozyme] — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dornase Alfa Inhalant Solution [Pulmozyme] (Dornase Alfa Inhalant Solution [Pulmozyme]) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Recombinant enzyme. Area: Pulmonology / Respiratory.

phase 3 Recombinant enzyme Extracellular DNA (deoxyribonucleic acid) Pulmonology / Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

Dornase Alfa Inhalant Solution [Pulmozyme] (Dornase Alfa Inhalant Solution [Pulmozyme]) — University Hospital, Strasbourg, France. Dornase alfa is a recombinant human deoxyribonuclease that cleaves extracellular DNA in airway secretions, reducing mucus viscosity and improving clearance.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Dornase Alfa Inhalant Solution [Pulmozyme] TARGET	Dornase Alfa Inhalant Solution [Pulmozyme]	University Hospital, Strasbourg, France	phase 3	Recombinant enzyme	Extracellular DNA (deoxyribonucleic acid)
recAP	recAP	AM-Pharma	marketed	Recombinant enzyme	Lipopolysaccharide (LPS) and pathogen-associated molecular patterns (PAMPs)
DNase	DNase	The Hospital for Sick Children	marketed	Recombinant enzyme	Deoxyribonucleic acid (DNA)
Pulmozyme®	Pulmozyme®	AO GENERIUM	marketed	Recombinant enzyme	Extracellular DNA
rhDNAse	rhDNAse	The Hospital for Sick Children	marketed	Recombinant enzyme	Extracellular DNA (deoxyribonucleic acid)
Dornase alfa (Pulmozyme)	Dornase alfa (Pulmozyme)	University of Jena	marketed	Recombinant enzyme	Extracellular DNA (deoxyribonucleic acid)
Fabrazyme (agalsidase beta)	Fabrazyme (agalsidase beta)	Genzyme, a Sanofi Company	marketed	Enzyme replacement therapy (ERT); recombinant enzyme	α-galactosidase A (GLA gene product); substrate: globotriaosylceramide (GL-3)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Recombinant enzyme class)

The Hospital for Sick Children · 2 drugs in this class
AO GENERIUM · 1 drug in this class
Fondation Ophtalmologique Adolphe de Rothschild · 1 drug in this class
Protalix · 1 drug in this class
University Hospital, Strasbourg, France · 1 drug in this class
University of Jena · 1 drug in this class
AM-Pharma · 1 drug in this class
University of Missouri-Columbia · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dornase Alfa Inhalant Solution [Pulmozyme] — Competitive Intelligence Brief. https://druglandscape.com/ci/dornase-alfa-inhalant-solution-pulmozyme. Accessed 2026-05-17.

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