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Doravirine/Lamivudine/Tenofovir — Competitive Intelligence Brief
phase 3
Antiretroviral combination (NNRTI + NRTI + NtRTI)
HIV reverse transcriptase
Infectious Disease / Virology
Small molecule
Live · refreshed every 30 min
Target snapshot
Doravirine/Lamivudine/Tenofovir (Doravirine/Lamivudine/Tenofovir) — Thomas Jefferson University. This fixed-dose combination inhibits HIV reverse transcriptase and integrase to block viral replication.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Doravirine/Lamivudine/Tenofovir TARGET | Doravirine/Lamivudine/Tenofovir | Thomas Jefferson University | phase 3 | Antiretroviral combination (NNRTI + NRTI + NtRTI) | HIV reverse transcriptase | |
| Emtricitabine / Tenofovir | Emtricitabine / Tenofovir | The Miriam Hospital | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor (NRTI/NtRTI) combination | HIV reverse transcriptase | |
| CAR | CAR | ViiV Healthcare | marketed | Antiretroviral combination therapy (INSTI + NNRTI) | HIV integrase and HIV reverse transcriptase | |
| Truvada Pill | Truvada Pill | University of North Carolina, Chapel Hill | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) combination | HIV reverse transcriptase | |
| 3TC | 3TC | Avexa | marketed | Nucleoside reverse transcriptase inhibitor (NRTI) | HIV reverse transcriptase; hepatitis B polymerase | |
| tenofovir disproxil fumarate/emtricitabine | tenofovir disproxil fumarate/emtricitabine | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Nucleoside/nucleotide reverse transcriptase inhibitor combination | HIV reverse transcriptase | |
| dolutegravir/abacavir/lamivudine | dolutegravir/abacavir/lamivudine | University College Dublin | marketed | Antiretroviral combination (INSTI + NRTIs) | HIV integrase, HIV reverse transcriptase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antiretroviral combination (NNRTI + NRTI + NtRTI) class)
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections · 1 drug in this class
- Thomas Jefferson University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Doravirine/Lamivudine/Tenofovir — Competitive Intelligence Brief. https://druglandscape.com/ci/doravirine-lamivudine-tenofovir. Accessed 2026-05-18.
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