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DMB-I (INN: Latrepirdine) — Competitive Intelligence Brief
phase 3
Neuroprotective agent
NMDA receptor, mitochondrial membrane, monoamine oxidase
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
DMB-I (INN: Latrepirdine) (DMB-I (INN: Latrepirdine)) — Bigespas LTD. Latrepirdine is a neuroprotective agent that modulates mitochondrial function and reduces neuronal excitotoxicity through multiple pathways including NMDA receptor antagonism and monoamine oxidase inhibition.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DMB-I (INN: Latrepirdine) TARGET | DMB-I (INN: Latrepirdine) | Bigespas LTD | phase 3 | Neuroprotective agent | NMDA receptor, mitochondrial membrane, monoamine oxidase | |
| Butylphthalide Soft Capsules | Butylphthalide Soft Capsules | Peking Union Medical College Hospital | marketed | Neuroprotective agent | ||
| NeuroAiD | NeuroAiD | CHIMES Society | marketed | Herbal neuroprotective agent | ||
| Citicoline eye drops 2% | Citicoline eye drops 2% | Omikron Italia S.r.l. | phase 3 | Neuroprotective agent / Membrane repair agent | Phospholipid synthesis pathway (CDP-choline pathway) | |
| EGb761 | EGb761 | Ipsen | phase 3 | Herbal extract / Neuroprotective agent | ||
| Edaravone Dexborneol Sequential Therapy | Edaravone Dexborneol Sequential Therapy | Simcere Pharmaceutical Co., Ltd | phase 3 | Neuroprotective agent combination | ||
| Riluzole (100 mg) | Riluzole (100 mg) | AB Science | phase 3 | Glutamate antagonist / Neuroprotective agent | Glutamate release (presynaptic); voltage-gated sodium channels |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Neuroprotective agent class)
- Bigespas LTD · 1 drug in this class
- Capital Medical University · 1 drug in this class
- Peking Union Medical College Hospital · 1 drug in this class
- Rong Hu, MD · 1 drug in this class
- Sanofi · 1 drug in this class
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Cite this brief
Drug Landscape (2026). DMB-I (INN: Latrepirdine) — Competitive Intelligence Brief. https://druglandscape.com/ci/dmb-i-inn-latrepirdine. Accessed 2026-05-17.
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