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DMB-I (INN: Latrepirdine) — Competitive Intelligence Brief

DMB-I (INN: Latrepirdine) (DMB-I (INN: Latrepirdine)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Neuroprotective agent. Area: Neurology.

phase 3 Neuroprotective agent NMDA receptor, mitochondrial membrane, monoamine oxidase Neurology Small molecule Live · refreshed every 30 min

Target snapshot

DMB-I (INN: Latrepirdine) (DMB-I (INN: Latrepirdine)) — Bigespas LTD. Latrepirdine is a neuroprotective agent that modulates mitochondrial function and reduces neuronal excitotoxicity through multiple pathways including NMDA receptor antagonism and monoamine oxidase inhibition.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DMB-I (INN: Latrepirdine) TARGET DMB-I (INN: Latrepirdine) Bigespas LTD phase 3 Neuroprotective agent NMDA receptor, mitochondrial membrane, monoamine oxidase
Butylphthalide Soft Capsules Butylphthalide Soft Capsules Peking Union Medical College Hospital marketed Neuroprotective agent
NeuroAiD NeuroAiD CHIMES Society marketed Herbal neuroprotective agent
Citicoline eye drops 2% Citicoline eye drops 2% Omikron Italia S.r.l. phase 3 Neuroprotective agent / Membrane repair agent Phospholipid synthesis pathway (CDP-choline pathway)
EGb761 EGb761 Ipsen phase 3 Herbal extract / Neuroprotective agent
Edaravone Dexborneol Sequential Therapy Edaravone Dexborneol Sequential Therapy Simcere Pharmaceutical Co., Ltd phase 3 Neuroprotective agent combination
Riluzole (100 mg) Riluzole (100 mg) AB Science phase 3 Glutamate antagonist / Neuroprotective agent Glutamate release (presynaptic); voltage-gated sodium channels

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Neuroprotective agent class)

  1. Bigespas LTD · 1 drug in this class
  2. Capital Medical University · 1 drug in this class
  3. Peking Union Medical College Hospital · 1 drug in this class
  4. Rong Hu, MD · 1 drug in this class
  5. Sanofi · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DMB-I (INN: Latrepirdine) — Competitive Intelligence Brief. https://druglandscape.com/ci/dmb-i-inn-latrepirdine. Accessed 2026-05-17.

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