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Renal transplant rejection — Treatment Landscape & Competitive Intelligence
10 marketed
0 Phase 3
0 Phase 2
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Marketed treatment landscape
| Drug | Generic | Sponsor | Class | Target | Line of therapy | First approval |
|---|---|---|---|---|---|---|
| Ides | IMLIFIDASE | Hansa Biopharma AB | Immunoglobulin gamma (IgG), heavy chain | 2020-01-01 | ||
| Nulojix | BELATACEPT | Bristol-Myers Squibb | Selective T Cell Costimulation Blocker [EPC] | T-lymphocyte activation antigen CD80 | 2011-01-01 | |
| Chrft5 | BASILIXIMAB | Novartis | Interleukin-2 Receptor Blocking Antibody [EPC] | Interleukin-2 receptor subunit alpha | 1998-01-01 | |
| Zenapax | DACLIZUMAB | Hoffman-La Roche | Interleukin-2 Receptor Blocking Antibody | Interleukin-2 receptor | 1997-01-01 | |
| Prograf | TACROLIMUS | Astellas Pharma | Calcineurin Inhibitor Immunosuppressant | Interferon gamma | 1994-01-01 | |
| Orthoclone Okt3 | MUROMONAB-CD3 | Ortho Biotech | CD3 Blocker Immunosuppressant | T-cell surface glycoprotein CD3 | 1992-01-01 | |
| Simulect | Simulect | Astellas Pharma Inc | Interleukin-2 receptor subunit alpha | |||
| Nulojix | Nulojix | Bristol-Myers Squibb | T-lymphocyte activation antigen CD80, T-lymphocyte activation antigen CD86 | |||
| Zenapax | Zenapax | National Institute of Neurological Disorders and Stroke (NINDS) | Interleukin-2 receptor | |||
| Muromonab | Muromonab | St. Jude Children's Research Hospital | T-cell surface glycoprotein CD3 |
Phase 3 pipeline
Phase 2 pipeline
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Sponsor landscape
- Bristol-Myers Squibb · 2 drugs in Renal transplant rejection
- Astellas Pharma Inc · 1 drug in Renal transplant rejection
- Hansa Biopharma AB · 1 drug in Renal transplant rejection
- Hoffman-La Roche · 1 drug in Renal transplant rejection
- National Institute of Neurological Disorders and Stroke (NINDS) · 1 drug in Renal transplant rejection
- Novartis · 1 drug in Renal transplant rejection
- Ortho Biotech · 1 drug in Renal transplant rejection
- Astellas Pharma · 1 drug in Renal transplant rejection
- St. Jude Children's Research Hospital · 1 drug in Renal transplant rejection
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Cite this brief
Drug Landscape (2026). Renal transplant rejection — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/renal-transplant-rejection. Accessed 2026-06-09.
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