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Pulmonary hypertension — Treatment Landscape & Competitive Intelligence

Pulmonary hypertension (disease) competitive landscape: 6 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

6 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Pulmonary hypertension, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Tracleer BOSENTAN AstraZeneca Endothelin Receptor Antagonist Endothelin-1 receptor 2001-01-01
Inomax NITRIC OXIDE Vero Biotech Inc Standardized Chemical Allergen [EPC] Soluble guanylate cyclase 1999-01-01
Flolan EPOPROSTENOL AstraZeneca Prostacycline Vasodilator [EPC] Prostacyclin receptor 1995-01-01
Cialis tadalafil Eli Lilly Phosphodiesterase 5 Inhibitor [EPC] Nuclear receptor subfamily 2 group E member 1, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, Potassium voltage-gated channel subfamily H member 2
prostacyclin prostacyclin United Therapeutics P2Y purinoceptor 12, Prostacyclin receptor, Prostaglandin E2 receptor EP1 subtype
Cialis Cialis Ottawa Hospital Research Institute Nuclear receptor subfamily 2 group E member 1, Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A, Potassium voltage-gated channel subfamily H member 2

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. AstraZeneca · 2 drugs in Pulmonary hypertension
  2. Eli Lilly · 1 drug in Pulmonary hypertension
  3. Ottawa Hospital Research Institute · 1 drug in Pulmonary hypertension
  4. United Therapeutics · 1 drug in Pulmonary hypertension
  5. Vero Biotech Inc · 1 drug in Pulmonary hypertension

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Every new regulatory action, PDUFA date, or trial completion in Pulmonary hypertension:

Cite this brief

Drug Landscape (2026). Pulmonary hypertension — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/pulmonary-hypertension. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing