How many drugs treat Opioid dependence?

Drug Landscape tracks 4 marketed treatments for Opioid dependence (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

Opioid dependence — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Opioid dependence (disease) competitive landscape: 4 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

4 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Opioid dependence, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Orlaam	LEVOMETHADYL ACETATE	Roxane	High Risk QT Prolonging Agents	Potassium voltage-gated channel subfamily H member 2	1993-01-01
Subutex	Buprenorphine Hydrochloride	Indivior	partial opioid agonist	mu-opioid receptor, kappa-opioid receptor	1981-01-01
Subutex	BUPRENORPHINE	Purdue Pharma Lp	Partial Opioid Agonist	mu-opioid receptor, kappa-opioid receptor	1981-01-01
Narcan	NALOXONE	Adapt	Opioid Antagonist	Mu-type opioid receptor	1971-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

· 2 drugs in Opioid dependence
Adapt · 1 drug in Opioid dependence
Indivior · 1 drug in Opioid dependence
Purdue Pharma Lp · 1 drug in Opioid dependence
Roxane · 1 drug in Opioid dependence

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Every new regulatory action, PDUFA date, or trial completion in Opioid dependence:

Cite this brief

Drug Landscape (2026). Opioid dependence — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/opioid-dependence. Accessed 2026-06-10.

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