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Nasal congestion — Treatment Landscape & Competitive Intelligence

Nasal congestion (disease) competitive landscape: 10 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

10 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Nasal congestion, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Clarinex desloratadine Generic (originally Schering-Plough/MSD) Histamine-1 Receptor Antagonist [EPC] 5-hydroxytryptamine receptor 6, Histamine H4 receptor, Multidrug resistance protein 1 2001-12-21
Propadrine PHENYLPROPANOLAMINE Alpharma Us Pharms Indirectly Acting Sympathomimetic Amines Sodium-dependent noradrenaline transporter 2000-01-01
Zyrtec cetirizine Generic (originally UCB Pharma) Second-generation antihistamine Angiopoietin-1 receptor, Histamine H1 receptor, Potassium voltage-gated channel subfamily H member 2 1995-09-29
Flolan EPOPROSTENOL AstraZeneca Prostacycline Vasodilator [EPC] Prostacyclin receptor 1995-01-01
Semprex-D ACRIVASTINE Auxilium Pharms Inc Histamine-1 Receptor Antagonist Histamine H1 receptor 1994-01-01
Claritin loratadine Generic (originally Schering-Plough) Second-generation antihistamine Sodium-dependent neutral amino acid transporter B(0)AT2, Cytochrome P450 2C19, Multidrug resistance protein 1 1993-04-12
Phenazoline ANTAZOLINE Novartis antazoline Histamine H1 receptor 1990-01-01
Marezine CYCLIZINE GSK cyclizine Histamine H1 receptor 1982-01-01
Hispril DIPHENYLPYRALINE GSK diphenylpyraline Histamine H1 receptor 1982-01-01
Bss SODIUM CITRATE B Braun sodium citrate Calcium 1980-01-01

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. · 20 drugs in Nasal congestion
  2. Generic (multiple manufacturers) · 4 drugs in Nasal congestion
  3. Bayer · 2 drugs in Nasal congestion
  4. Fougera Pharms · 2 drugs in Nasal congestion
  5. GSK · 2 drugs in Nasal congestion
  6. B Braun · 2 drugs in Nasal congestion
  7. Novartis · 2 drugs in Nasal congestion
  8. Auxilium Pharms Inc · 1 drug in Nasal congestion
  9. Allergan/AbbVie · 1 drug in Nasal congestion
  10. Chattem · 1 drug in Nasal congestion
  11. Caraco · 1 drug in Nasal congestion
  12. AstraZeneca · 1 drug in Nasal congestion

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Every new regulatory action, PDUFA date, or trial completion in Nasal congestion:

Cite this brief

Drug Landscape (2026). Nasal congestion — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/nasal-congestion. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing