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Metastatic renal cell carcinoma — Treatment Landscape & Competitive Intelligence

Metastatic renal cell carcinoma (disease) competitive landscape: 9 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

9 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Metastatic renal cell carcinoma, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Opdivo nivolumab Bristol-Myers Squibb Programmed Death Receptor-1 Blocking Antibody [EPC] Programmed cell death protein 1 2014-01-01
Cometriq Cabometyx Exelixis Kinase Inhibitor Vascular endothelial growth factor receptor 2 2012-01-01
Cometriq CABOZANTINIB Exelixis Inc Kinase Inhibitor Vascular endothelial growth factor receptor 2 2012-01-01
Bevacizumab Bevacizumab-Bvzr Roche Monoclonal antibody Vascular Endothelial Growth Factor (VEGF) 2004-01-01
Avastin bevacizumab Roche Vascular Endothelial Growth Factor Inhibitor [EPC] Vascular endothelial growth factor A 2004-01-01
Proleukin ALDESLEUKIN Chiron Lymphocyte Growth Factor [EPC] Interleukin-2 receptor 1992-01-01
Proleukin Proleukin University of Minnesota Interleukin-2 receptor
Pembrolizuma Pembrolizuma Memorial Sloan Kettering Cancer Center Programmed cell death protein 1
Avastin Avastin Washington University School of Medicine Vascular endothelial growth factor A

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. Roche · 2 drugs in Metastatic renal cell carcinoma
  2. Chiron · 1 drug in Metastatic renal cell carcinoma
  3. Exelixis · 1 drug in Metastatic renal cell carcinoma
  4. Exelixis Inc · 1 drug in Metastatic renal cell carcinoma
  5. Memorial Sloan Kettering Cancer Center · 1 drug in Metastatic renal cell carcinoma
  6. University of Minnesota · 1 drug in Metastatic renal cell carcinoma
  7. Bristol-Myers Squibb · 1 drug in Metastatic renal cell carcinoma
  8. Washington University School of Medicine · 1 drug in Metastatic renal cell carcinoma

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Every new regulatory action, PDUFA date, or trial completion in Metastatic renal cell carcinoma:

Cite this brief

Drug Landscape (2026). Metastatic renal cell carcinoma — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/metastatic-renal-cell-carcinoma. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing