How many drugs treat fatigue?

Drug Landscape tracks 8 marketed treatments for fatigue (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

fatigue — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

fatigue (disease) competitive landscape: 8 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

8 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating fatigue, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Immune Support	CORTISONE	Merck	Non-Standardized Plant Allergenic Extract [EPC]		1974-01-01
Pollutox	OZONE	Deseret Biologicals, Inc.	Radiographic Contrast Agent [EPC]
Influenza	Influenza and COVID-19 Combination A	BioNTech	Non-Standardized Plant Allergenic Extract [EPC]	SARS-CoV-2 spike protein and influenza hemagglutinin protein
Multi-Phenolic	PIPERINE	Energique, Inc.	Vitamin C [EPC]
Influenza	Influenza and COVID-19 Combination B	BioNTech	Non-Standardized Plant Allergenic Extract [EPC]	Not specified
Post - Vaccination	vaccination	Pfizer	Inactivated Poliovirus Vaccine [EPC]	Immune system
Multi-Phenolic	PYRROLE	Energique, Inc.	Vitamin C [EPC]
Aspartame/MSG Detox	MALTODEXTRIN	Deseret Biologicals, Inc.	Standardized Chemical Allergen [EPC]

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

BioNTech · 2 drugs in fatigue
Deseret Biologicals, Inc. · 2 drugs in fatigue
Energique, Inc. · 2 drugs in fatigue
Merck · 1 drug in fatigue
Pfizer · 1 drug in fatigue

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Cite this brief

Drug Landscape (2026). fatigue — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/fatigue. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing