How many drugs treat Diarrhea?

Drug Landscape tracks 6 marketed treatments for Diarrhea (deduplicated by molecule). 0 Phase 3 candidates and 0 Phase 2 candidates are in the pipeline.

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Last reviewed 2026-06-10 · How we verify

Diarrhea — Treatment Landscape & Competitive Intelligence

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Diarrhea (disease) competitive landscape: 6 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

6 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Diarrhea, deduplicated by molecule. See the full disease page for line-of-therapy detail.

Drug	Generic	Sponsor	Class	Target	First approval
Motofen	DIFENOXIN	Sebela Ireland Ltd	Antidiarrheal	Mu-type opioid receptor	1978-01-01
Imodium	loperamide	Johnson & Johnson (McNeil Consumer Healthcare)	Antidiarrheal (peripheral opioid agonist)	Aldehyde oxidase, Cocaine esterase, D(4) dopamine receptor	1976-12-28
Lomotil	DIPHENOXYLATE	Pfizer	Antidiarrheal	Mu-type opioid receptor	1960-01-01
MS Contin	morphine sulfate	Generic (multiple manufacturers)	Opioid analgesic	Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor	1941-01-01
Pepto-Bismol	bismuth subsalicylate	Generic (Procter & Gamble)	Bismuth [EPC]	Cyclooxygenase	1939-01-01
Xermelo	Xermelo	TerSera Therapeutics LLC		Tryptophan 5-hydroxylase 1

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

Pfizer · 2 drugs in Diarrhea
Generic (Procter & Gamble) · 1 drug in Diarrhea
Generic (multiple manufacturers) · 1 drug in Diarrhea
Johnson & Johnson (McNeil Consumer Healthcare) · 1 drug in Diarrhea
Sebela Ireland Ltd · 1 drug in Diarrhea
TerSera Therapeutics LLC · 1 drug in Diarrhea

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Every new regulatory action, PDUFA date, or trial completion in Diarrhea:

Cite this brief

Drug Landscape (2026). Diarrhea — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/diarrhea. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing