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Chronic graft-versus-host disease — Treatment Landscape & Competitive Intelligence

Chronic graft-versus-host disease (disease) competitive landscape: 3 marketed treatments tracked, 0 Phase 3 candidates, 0 Phase 2 candidates. Recent regulatory actions and upcoming PDUFA dates across the entire treatment set.

3 marketed 0 Phase 3 0 Phase 2 Live · 30-min refresh

Marketed treatment landscape

Approved drugs treating Chronic graft-versus-host disease, deduplicated by molecule. See the full disease page for line-of-therapy detail.

DrugGenericSponsorClassTargetLine of therapyFirst approval
Imbruvica ibrutinib AbbVie Kinase Inhibitor [EPC] Tyrosine-protein kinase Blk 2013-01-01
Jakafi RUXOLITINIB Incyte Corp Ankyrin repeat and protein kinase domain-containing protein 1, Bone morphogenetic protein receptor type-1B, Calcium/calmodulin-dependent protein kinase type IV 2011-01-01
Imbruvica Imbruvica Rabin Medical Center Nuclear receptor subfamily 4 group A member 3, Platelet glycoprotein VI, Serine/threonine-protein kinase LATS1

Phase 3 pipeline

No Phase 3 pipeline candidates tracked.

Phase 2 pipeline

No Phase 2 pipeline candidates tracked.

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this treatment set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this treatment set.

Sponsor landscape

  1. AbbVie · 1 drug in Chronic graft-versus-host disease
  2. Incyte Corp · 1 drug in Chronic graft-versus-host disease
  3. Rabin Medical Center · 1 drug in Chronic graft-versus-host disease

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Every new regulatory action, PDUFA date, or trial completion in Chronic graft-versus-host disease:

Cite this brief

Drug Landscape (2026). Chronic graft-versus-host disease — Treatment Landscape & Competitive Intelligence Brief. https://druglandscape.com/ci/disease/chronic-graft-versus-host-disease. Accessed 2026-06-10.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing