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Direct Acting Antivirals — Competitive Intelligence Brief

Direct Acting Antivirals (Direct Acting Antivirals) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Direct-acting antiviral (DAA). Area: Virology/Infectious Disease.

marketed Direct-acting antiviral (DAA) Virology/Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

Direct Acting Antivirals (Direct Acting Antivirals) — Medical University of Warsaw. Direct-acting antivirals inhibit viral enzymes or proteins required for viral replication, preventing the virus from multiplying within host cells.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Direct Acting Antivirals TARGET Direct Acting Antivirals Medical University of Warsaw marketed Direct-acting antiviral (DAA)
Daclatasvir + Sofosbuvir Daclatasvir + Sofosbuvir Federal University of São Paulo marketed Direct-acting antiviral (DAA) combination HCV NS5A protein and HCV NS5B RNA-dependent RNA polymerase
Clinically prescribed direct acting antiviral Clinically prescribed direct acting antiviral Massachusetts General Hospital marketed Direct-acting antiviral (DAA)
Sofosbuvir and Velpatasvir Sofosbuvir and Velpatasvir Hannover Medical School marketed Direct-acting antiviral (DAA) combination HCV NS5B polymerase and NS5A protein
Daclinza and Sunvepra Daclinza and Sunvepra Pusan National University Hospital marketed Direct-acting antiviral (DAA) combination HCV NS5A protein and HCV NS5B RNA-dependent RNA polymerase
Zepatier plus Sofosbuvir Zepatier plus Sofosbuvir Massachusetts General Hospital marketed Direct-acting antiviral (DAA) combination HCV NS5A, NS3/4A protease, NS5B RNA polymerase
Sofosbuvir / Velpatasvir Sofosbuvir / Velpatasvir Peking University First Hospital marketed Direct-acting antiviral (DAA) combination HCV NS5B polymerase and NS5A protein

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Direct-acting antiviral (DAA) class)

  1. Massachusetts General Hospital · 1 drug in this class
  2. Medical University of Warsaw · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Direct Acting Antivirals — Competitive Intelligence Brief. https://druglandscape.com/ci/direct-acting-antivirals. Accessed 2026-05-17.

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