Last reviewed · How we verify
Direct Acting Antivirals — Competitive Intelligence Brief
marketed
Direct-acting antiviral (DAA)
Virology/Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Direct Acting Antivirals (Direct Acting Antivirals) — Medical University of Warsaw. Direct-acting antivirals inhibit viral enzymes or proteins required for viral replication, preventing the virus from multiplying within host cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Direct Acting Antivirals TARGET | Direct Acting Antivirals | Medical University of Warsaw | marketed | Direct-acting antiviral (DAA) | ||
| Daclatasvir + Sofosbuvir | Daclatasvir + Sofosbuvir | Federal University of São Paulo | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A protein and HCV NS5B RNA-dependent RNA polymerase | |
| Clinically prescribed direct acting antiviral | Clinically prescribed direct acting antiviral | Massachusetts General Hospital | marketed | Direct-acting antiviral (DAA) | ||
| Sofosbuvir and Velpatasvir | Sofosbuvir and Velpatasvir | Hannover Medical School | marketed | Direct-acting antiviral (DAA) combination | HCV NS5B polymerase and NS5A protein | |
| Daclinza and Sunvepra | Daclinza and Sunvepra | Pusan National University Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A protein and HCV NS5B RNA-dependent RNA polymerase | |
| Zepatier plus Sofosbuvir | Zepatier plus Sofosbuvir | Massachusetts General Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A, NS3/4A protease, NS5B RNA polymerase | |
| Sofosbuvir / Velpatasvir | Sofosbuvir / Velpatasvir | Peking University First Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS5B polymerase and NS5A protein |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Direct-acting antiviral (DAA) class)
- Massachusetts General Hospital · 1 drug in this class
- Medical University of Warsaw · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- Direct Acting Antivirals CI watch — RSS
- Direct Acting Antivirals CI watch — Atom
- Direct Acting Antivirals CI watch — JSON
- Direct Acting Antivirals alone — RSS
- Whole Direct-acting antiviral (DAA) class — RSS
Cite this brief
Drug Landscape (2026). Direct Acting Antivirals — Competitive Intelligence Brief. https://druglandscape.com/ci/direct-acting-antivirals. Accessed 2026-05-17.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab