Who are Tecfidera's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Vumerity, Niaspan, Vumerity, Tecfidera, Comparator: niacin, ER-niacin.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Tecfidera — Competitive Intelligence Brief

Tecfidera (DIMETHYL FUMARATE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: dimethyl fumarate. Area: Immunology.

marketed dimethyl fumarate Hydroxycarboxylic acid receptor 2 Immunology Small molecule Live · refreshed every 30 min

Target snapshot

Tecfidera (DIMETHYL FUMARATE) — Biogen. Tecfidera works by activating the hydroxycarboxylic acid receptor 2, which helps to reduce inflammation and modulate the immune system.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Tecfidera TARGET	DIMETHYL FUMARATE	Biogen	marketed	dimethyl fumarate	Hydroxycarboxylic acid receptor 2	2013-01-01
Vumerity	DIROXIMEL FUMARATE	Biogen	marketed		Hydroxycarboxylic acid receptor 2	2019-01-01
Niaspan	Nicotinic Acid	Medpointe Pharm Hlc	marketed	Non-Standardized Food Allergenic Extract [EPC]	Hydroxycarboxylic acid receptor 2	1957-01-01
Vumerity	Vumerity	University of Nebraska	marketed		Nuclear factor erythroid 2-related factor 2, Hydroxycarboxylic acid receptor 2
Tecfidera	Tecfidera	EMD Serono Research & Development Institute, Inc.	marketed		Hydroxycarboxylic acid receptor 2, Kelch-like ECH-associated protein 1
Comparator: niacin	Comparator: niacin	Merck Sharp & Dohme LLC	phase 3	Lipid-modifying agent; B vitamin	GPR109A (hydroxycarboxylic acid receptor 2)
ER-niacin	ER-niacin	Merck Sharp & Dohme LLC	phase 3	Lipid-modifying agent; B-vitamin	DGAT2; GPR109A (hydroxycarboxylic acid receptor 2)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (dimethyl fumarate class)

Biogen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tecfidera — Competitive Intelligence Brief. https://druglandscape.com/ci/dimethyl-fumarate. Accessed 2026-05-14.

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