Who are Korsuva's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Remitch, Halflytely, Revex, Stadol Preservative Free, Codeine, MS Contin.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Korsuva — Competitive Intelligence Brief

Korsuva (DIFELIKEFALIN) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Kappa Opioid Receptor Agonist. Area: Neuroscience.

marketed Kappa Opioid Receptor Agonist Kappa-type opioid receptor Neuroscience Recombinant protein Live · refreshed every 30 min

Target snapshot

Korsuva (DIFELIKEFALIN) — Vifor Intl. Korsuva works by activating the kappa-type opioid receptor, which helps to reduce itching.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Korsuva TARGET	DIFELIKEFALIN	Vifor Intl	marketed	Kappa Opioid Receptor Agonist	Kappa-type opioid receptor	2021-01-01
Remitch	NALFURAFINE		marketed	nalfurafine	Kappa-type opioid receptor	2009-01-01
Halflytely	BISACODYL	Braintree	marketed	Stimulant Laxative [EPC]	Kappa-type opioid receptor	2004-01-01
Revex	NALMEFENE	Hikma	marketed	Opioid Antagonist	Kappa-type opioid receptor	1995-01-01
Stadol Preservative Free	BUTORPHANOL		marketed	Opioid Agonist/Antagonist	Kappa-type opioid receptor	1978-01-01
Codeine	codeine phosphate	Generic (multiple manufacturers)	marketed	Opioid analgesic, Antitussive	Delta-type opioid receptor, Kappa-type opioid receptor, Mu-type opioid receptor	1950-01-01
MS Contin	morphine sulfate	Generic (multiple manufacturers)	marketed	Opioid analgesic	Solute carrier family 22 member 1, Delta-type opioid receptor, Kappa-type opioid receptor	1941-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2028-08-12 — MS Contin · 7955619 · Formulation · US
2028-08-12 — MS Contin · 10314788 · Formulation · US
2033-07-01 — MS Contin · 9044402 · Formulation · US
2033-07-01 — MS Contin · 9549899 · Formulation · US
2034-03-12 — MS Contin · 9248229 · Formulation · US
2034-03-12 — MS Contin · 9192608 · Method of Use · US
2034-03-12 — MS Contin · 9072781 · Formulation · US

Sponsor landscape (Kappa Opioid Receptor Agonist class)

Vifor Intl · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Korsuva — Competitive Intelligence Brief. https://druglandscape.com/ci/difelikefalin. Accessed 2026-05-13.

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