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DFN-15 Dose 1 — Competitive Intelligence Brief

DFN-15 Dose 1 (DFN-15 Dose 1) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: 5-HT7 receptor antagonist. Area: Psychiatry/Neurology.

phase 2 5-HT7 receptor antagonist 5-HT7 receptor Psychiatry/Neurology Small molecule Live · refreshed every 30 min

Target snapshot

DFN-15 Dose 1 (DFN-15 Dose 1) — Dr. Reddy's Laboratories Limited. DFN-15 is a selective serotonin 5-HT7 receptor antagonist designed to modulate serotonergic neurotransmission.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
DFN-15 Dose 1 TARGET DFN-15 Dose 1 Dr. Reddy's Laboratories Limited phase 2 5-HT7 receptor antagonist 5-HT7 receptor
Latuda (Lurasidone) Latuda (Lurasidone) Massachusetts General Hospital marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT7 receptor
Latuda© Latuda© University of North Carolina, Chapel Hill marketed Atypical antipsychotic Dopamine D2 receptor, serotonin 5-HT7 receptor, serotonin 5-HT1A receptor
NRX-101 Oral Capsule NRX-101 Oral Capsule NeuroRx, Inc. phase 3 Fixed-dose combination (NMDA receptor modulator + atypical antipsychotic) NMDA receptor (d-cycloserine component); dopamine D2 receptor and serotonin 5-HT7 receptor (lurasidone component)
Vortioxetine tablets Vortioxetine tablets Takeda phase 3 Serotonin modulator and stimulator 5-HT3 receptor, 5-HT1A receptor, 5-HT7 receptor, norepinephrine transporter
OPC-34712 OPC-34712 Otsuka Pharmaceutical Development & Commercialization, Inc. phase 3 5-HT7 receptor antagonist 5-HT7 receptor
Phase 1: Aripiprazole Phase 1: Aripiprazole Shanghai Mental Health Center phase 3 Atypical antipsychotic Dopamine D2/D3 receptor (partial agonist); serotonin 5-HT1A and 5-HT7 receptors

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (5-HT7 receptor antagonist class)

  1. Otsuka Pharmaceutical Development & Commercialization, Inc. · 2 drugs in this class
  2. Dr. Reddy's Laboratories Limited · 1 drug in this class
  3. Eli Lilly and Company · 1 drug in this class
  4. Neumora Therapeutics, Inc. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). DFN-15 Dose 1 — Competitive Intelligence Brief. https://druglandscape.com/ci/dfn-15-dose-1. Accessed 2026-06-10.

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