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Zinecard — Competitive Intelligence Brief
marketed
Cytoprotective Agent
DNA topoisomerase 2-alpha
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Zinecard (DEXRAZOXANE) — Pfizer. Zinecard works by binding to metal ions and preventing them from causing damage to DNA during anthracycline treatment.
Comparator set (5 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Zinecard TARGET | DEXRAZOXANE | Pfizer | marketed | Cytoprotective Agent | DNA topoisomerase 2-alpha | 1995-01-01 |
| Idamycin Pfs | IDARUBICIN | marketed | Anthracycline Topoisomerase Inhibitor | DNA topoisomerase 2-alpha | 1990-01-01 | |
| Vepesid | etoposide | Bristol-Myers Squibb K.K. | marketed | Topoisomerase Inhibitor [EPC] | DNA topoisomerase 2-alpha | 1983-01-01 |
| Blenoxane | BLEOMYCIN | Bristol-Myers Squibb | marketed | Cytoprotective Agent | Aspartyl/asparaginyl beta-hydroxylase | 1973-01-01 |
| amifostine trihydrate | amifostine trihydrate | City of Hope Medical Center | marketed | Cytoprotective agent | ||
| BNP7787 | BNP7787 | Alliance for Clinical Trials in Oncology | phase 3 | Cytoprotective agent / Cisplatin protectant | Cisplatin (indirect; forms inactivating complex) |
Recent regulatory actions (last 90 days)
- — Vepesid · FDA · approved · US · Bristol-Myers Squibb K.K.
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Cytoprotective Agent class)
- Bristol-Myers Squibb · 1 drug in this class
- Pfizer · 1 drug in this class
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- Zinecard CI watch — RSS
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- Whole Cytoprotective Agent class — RSS
Cite this brief
Drug Landscape (2026). Zinecard — Competitive Intelligence Brief. https://druglandscape.com/ci/dexrazoxane. Accessed 2026-05-13.
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