Who are Depakote DR's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Duvyzat, Farydak, Beleodaq, BELINOSTAT, Istodax, Zolinza.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-15 · How we verify

Depakote DR — Competitive Intelligence Brief

Depakote DR (Depakote DR) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anticonvulsant; mood stabilizer; histone deacetylase inhibitor. Area: Neurology; Psychiatry.

marketed Anticonvulsant; mood stabilizer; histone deacetylase inhibitor GABA synthesis/metabolism; histone deacetylase Neurology; Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

Depakote DR (Depakote DR) — Massachusetts General Hospital. Depakote DR (divalproex sodium delayed-release) increases brain GABA levels and inhibits histone deacetylase, stabilizing neuronal membranes and reducing abnormal electrical activity.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Depakote DR TARGET	Depakote DR	Massachusetts General Hospital	marketed	Anticonvulsant; mood stabilizer; histone deacetylase inhibitor	GABA synthesis/metabolism; histone deacetylase
Duvyzat	GIVINOSTAT	Italfarmaco Spa	marketed	Histone Deacetylase Inhibitor [EPC]		2024-01-01
Farydak	PANOBINOSTAT	Secura	marketed	Histone Deacetylase Inhibitor	Histone deacetylase 4	2015-01-01
Beleodaq	belinostat	Acrotech Biopharma	marketed	Histone Deacetylase Inhibitor [EPC]	Histone deacetylase 1	2014-01-01
BELINOSTAT	BELINOSTAT		marketed	Histone Deacetylase Inhibitor [EPC]		2014-01-01
Istodax	ROMIDEPSIN	Teva Pharms Usa Inc	marketed	Histone Deacetylase Inhibitor	HDACs	2009-01-01
Zolinza	VORINOSTAT	Merck & Co.	marketed	Histone Deacetylase Inhibitor [EPC]	Histone deacetylase 6	2006-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anticonvulsant; mood stabilizer; histone deacetylase inhibitor class)

Massachusetts General Hospital · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Depakote DR — Competitive Intelligence Brief. https://druglandscape.com/ci/depakote-dr. Accessed 2026-05-15.

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