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Daprodustat (GSK1278863) — Competitive Intelligence Brief

Daprodustat (GSK1278863) (Daprodustat (GSK1278863)) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: HIF prolyl hydroxylase inhibitor. Area: Hematology.

phase 3 HIF prolyl hydroxylase inhibitor Prolyl hydroxylase domain-containing proteins (PHD) Hematology Small molecule Live · refreshed every 30 min

Target snapshot

Daprodustat (GSK1278863) (Daprodustat (GSK1278863)) — GlaxoSmithKline. Daprodustat inhibits hypoxia-inducible factor prolyl hydroxylase (HIF-PH), stabilizing HIF and increasing endogenous erythropoietin production to treat anemia.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Daprodustat (GSK1278863) TARGET Daprodustat (GSK1278863) GlaxoSmithKline phase 3 HIF prolyl hydroxylase inhibitor Prolyl hydroxylase domain-containing proteins (PHD)
Daprodustat large Daprodustat large GlaxoSmithKline phase 3 HIF prolyl hydroxylase inhibitor Prolyl hydroxylase (PHD)
Daprodustat tablets Daprodustat tablets GlaxoSmithKline phase 3 HIF prolyl hydroxylase inhibitor Hypoxia-inducible factor prolyl hydroxylase (HIF-PH)
Daprodustat small Daprodustat small GlaxoSmithKline phase 3 HIF prolyl hydroxylase inhibitor Prolyl hydroxylase domain-containing proteins (PHD)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (HIF prolyl hydroxylase inhibitor class)

  1. GlaxoSmithKline · 4 drugs in this class

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Cite this brief

Drug Landscape (2026). Daprodustat (GSK1278863) — Competitive Intelligence Brief. https://druglandscape.com/ci/daprodustat-gsk1278863. Accessed 2026-05-18.

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