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Daprodustat (GSK1278863) — Competitive Intelligence Brief
phase 3
HIF prolyl hydroxylase inhibitor
Prolyl hydroxylase domain-containing proteins (PHD)
Hematology
Small molecule
Live · refreshed every 30 min
Target snapshot
Daprodustat (GSK1278863) (Daprodustat (GSK1278863)) — GlaxoSmithKline. Daprodustat inhibits hypoxia-inducible factor prolyl hydroxylase (HIF-PH), stabilizing HIF and increasing endogenous erythropoietin production to treat anemia.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Daprodustat (GSK1278863) TARGET | Daprodustat (GSK1278863) | GlaxoSmithKline | phase 3 | HIF prolyl hydroxylase inhibitor | Prolyl hydroxylase domain-containing proteins (PHD) | |
| Daprodustat large | Daprodustat large | GlaxoSmithKline | phase 3 | HIF prolyl hydroxylase inhibitor | Prolyl hydroxylase (PHD) | |
| Daprodustat tablets | Daprodustat tablets | GlaxoSmithKline | phase 3 | HIF prolyl hydroxylase inhibitor | Hypoxia-inducible factor prolyl hydroxylase (HIF-PH) | |
| Daprodustat small | Daprodustat small | GlaxoSmithKline | phase 3 | HIF prolyl hydroxylase inhibitor | Prolyl hydroxylase domain-containing proteins (PHD) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (HIF prolyl hydroxylase inhibitor class)
- GlaxoSmithKline · 4 drugs in this class
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Cite this brief
Drug Landscape (2026). Daprodustat (GSK1278863) — Competitive Intelligence Brief. https://druglandscape.com/ci/daprodustat-gsk1278863. Accessed 2026-05-18.
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