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Dalcetrapib (RO4607381) — Competitive Intelligence Brief

Dalcetrapib (RO4607381) (Dalcetrapib (RO4607381)) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CETP inhibitor. Area: Cardiovascular.

phase 3 CETP inhibitor CETP (Cholesteryl ester transfer protein) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Dalcetrapib (RO4607381) (Dalcetrapib (RO4607381)) — Hoffmann-La Roche. Dalcetrapib inhibits cholesteryl ester transfer protein (CETP) to increase HDL cholesterol and reduce LDL cholesterol levels.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Dalcetrapib (RO4607381) TARGET Dalcetrapib (RO4607381) Hoffmann-La Roche phase 3 CETP inhibitor CETP (Cholesteryl ester transfer protein)
Monotherapy obicetrapib Monotherapy obicetrapib NewAmsterdam Pharma phase 3 CETP inhibitor CETP (cholesterol ester transfer protein)
Placebo anacetrapib Placebo anacetrapib University of Oxford phase 3 CETP inhibitor cholesterol ester transfer protein (CETP)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CETP inhibitor class)

  1. Hoffmann-La Roche · 1 drug in this class
  2. NewAmsterdam Pharma · 1 drug in this class
  3. University of Oxford · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Dalcetrapib (RO4607381) — Competitive Intelligence Brief. https://druglandscape.com/ci/dalcetrapib-ro4607381. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing