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Daclatasvir and Asunaprevir — Competitive Intelligence Brief
phase 2
Direct-acting antiviral
HCV NS5A, HCV NS3/4A protease
Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
Daclatasvir and Asunaprevir (Daclatasvir and Asunaprevir) — Sang Gyune Kim. Daclatasvir and Asunaprevir are direct-acting antivirals that inhibit the HCV NS5A and NS3/4A proteases, respectively.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Daclatasvir and Asunaprevir TARGET | Daclatasvir and Asunaprevir | Sang Gyune Kim | phase 2 | Direct-acting antiviral | HCV NS5A, HCV NS3/4A protease | |
| SOF+RBV | SOF+RBV | Humanity and Health Research Centre | marketed | Direct-acting antiviral (DAA) combination | HCV NS5B RNA polymerase; viral replication machinery | |
| PTV/r/OBV/DSV | PTV/r/OBV/DSV | National Taiwan University Hospital | marketed | HCV direct-acting antiviral combination | HCV NS3/4A protease, NS5A, NS5B polymerase | |
| EXVIERA | EXVIERA | HaEmek Medical Center, Israel | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A, NS5B, NS3/4A protease | |
| Sofosbuvir/Velpatasvir + Ribavirin | Sofosbuvir/Velpatasvir + Ribavirin | Peking University People's Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS5B polymerase, HCV NS5A protein | |
| sofosbubir/velpatasvir/voxilaprevir | sofosbubir/velpatasvir/voxilaprevir | Partners in Health | marketed | Direct-acting antiviral (DAA) combination | HCV NS5B polymerase, NS5A protein, NS3/4A protease | |
| Combined therapy LDV and SOF | Combined therapy LDV and SOF | Yassin Abdelghaffar Charity Center for Liver Disease and Research | marketed | Direct-acting antiviral combination (NS5A inhibitor + nucleotide polymerase inhibitor) | HCV NS5A protein and HCV NS5B RNA-dependent RNA polymerase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Direct-acting antiviral class)
- Hospices Civils de Lyon · 1 drug in this class
- Iran Hepatitis Network · 1 drug in this class
- Qing XIe · 1 drug in this class
- Sang Gyune Kim · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Daclatasvir and Asunaprevir — Competitive Intelligence Brief. https://druglandscape.com/ci/daclatasvir-and-asunaprevir. Accessed 2026-05-18.
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