Last reviewed · How we verify
Cyclobenzaprine with caffeine — Competitive Intelligence Brief
phase 3
Skeletal muscle relaxant with CNS stimulant
Alpha-2 adrenergic receptors (cyclobenzaprine); adenosine receptors (caffeine)
Neurology / Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
Cyclobenzaprine with caffeine (Cyclobenzaprine with caffeine) — EMS. Cyclobenzaprine is a muscle relaxant that reduces muscle tension through central nervous system depression, while caffeine is a stimulant that counteracts sedation and enhances alertness.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Cyclobenzaprine with caffeine TARGET | Cyclobenzaprine with caffeine | EMS | phase 3 | Skeletal muscle relaxant with CNS stimulant | Alpha-2 adrenergic receptors (cyclobenzaprine); adenosine receptors (caffeine) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Skeletal muscle relaxant with CNS stimulant class)
- EMS · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Cyclobenzaprine with caffeine — Competitive Intelligence Brief. https://druglandscape.com/ci/cyclobenzaprine-with-caffeine. Accessed 2026-05-16.
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