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CTC-501 — Competitive Intelligence Brief
phase 2
CD47-SIRPα inhibitor
CD47
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CTC-501 (CTC-501) — Chase Therapeutics Corporation. CTC-501 is a CD47-SIRPα inhibitor, which works by blocking the interaction between CD47 and SIRPα on the surface of immune cells, thereby enhancing the immune system's ability to recognize and destroy cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CTC-501 TARGET | CTC-501 | Chase Therapeutics Corporation | phase 2 | CD47-SIRPα inhibitor | CD47 | |
| HP-802-247 | HP-802-247 | Healthpoint | phase 3 | CD47 antibody | CD47 | |
| MB-102 DMID | MB-102 DMID | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | phase 3 | monoclonal antibody | CD47 | |
| [68Ga]Ga-PentixaFor | [68Ga]Ga-PentixaFor | Nantes University Hospital | phase 3 | Radiopharmaceutical | CD47 | |
| Open single period A140 | Open single period A140 | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | phase 3 | CD47 inhibitor | CD47 | |
| mini CYVE, without 3 maintenance courses | mini CYVE, without 3 maintenance courses | Gustave Roussy, Cancer Campus, Grand Paris | phase 3 | CD47/SIRPα inhibitor | CD47 | |
| CHS-1420 | CHS-1420 | Coherus Oncology, Inc. | phase 3 | Bispecific antibody | CD47 and CD40 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (CD47-SIRPα inhibitor class)
- Chase Therapeutics Corporation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CTC-501 — Competitive Intelligence Brief. https://druglandscape.com/ci/ctc-501. Accessed 2026-05-13.
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