Who are CRS-207's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): CAR T cells, rondecabtagene autoleucel, Comirnaty, Prevnar 20, Tozinameran 12 Years of age and older, 15-valent pneumococcal conjugate vaccine (PCV15).

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Last reviewed 2026-05-13 · How we verify

CRS-207 — Competitive Intelligence Brief

CRS-207 (CRS-207) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: vaccine. Area: Oncology.

phase 2 vaccine mesothelin Oncology Biologic Live · refreshed every 30 min

Target snapshot

CRS-207 (CRS-207) — Aduro Biotech, Inc.. CRS-207 is a live, attenuated Listeria monocytogenes vaccine that stimulates an immune response against mesothelin.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
CRS-207 TARGET	CRS-207	Aduro Biotech, Inc.	phase 2	vaccine	mesothelin
CAR T cells	CAR T cells	Memorial Sloan Kettering Cancer Center	phase 3	CAR T cell therapy	Tumor-associated antigens (e.g., CD19, BCMA, mesothelin depending on construct)
rondecabtagene autoleucel	rondecabtagene autoleucel	Lyell Immunopharma, Inc.	phase 3	CAR-T cell therapy	Mesothelin (MSLN)
Comirnaty	BNT162b2 (tozinameran)	Pfizer Inc.	marketed	vaccine	SARS-CoV-2 virus	2021-08-23
Prevnar 20	pneumococcal 20-valent conjugate vaccine (PCV20)	Pfizer Inc.	marketed	Pneumococcal conjugate vaccine	Streptococcus pneumoniae capsular polysaccharides (20 serotypes)	2021-06-08
Tozinameran 12 Years of age and older	tozinameran-12-years-of-age-and-older	Pfizer	marketed	vaccine	SARS-CoV-2 spike protein
15-valent pneumococcal conjugate vaccine (PCV15)	15-valent-pneumococcal-conjugate-vaccine-pcv15	Pfizer	marketed	vaccine	Streptococcus pneumoniae

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2033-06-01 — Prevnar 20 · US 8,895,024 · Composition of matter · US
2035-06-01 — Prevnar 20 · US 10,279,033 · Method of use · US

Sponsor landscape (vaccine class)

Pfizer · 20 drugs in this class
Sanofi Pasteur, a Sanofi Company · 20 drugs in this class
GlaxoSmithKline · 12 drugs in this class
Merck Sharp & Dohme LLC · 12 drugs in this class
Centers for Disease Control and Prevention · 9 drugs in this class
Zhejiang Provincial Center for Disease Control and Prevention · 7 drugs in this class
Jiangsu Province Centers for Disease Control and Prevention · 6 drugs in this class
Beijing Center for Disease Control and Prevention · 6 drugs in this class
International Centre for Diarrhoeal Disease Research, Bangladesh · 5 drugs in this class
Sinovac Biotech Co., Ltd · 4 drugs in this class

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Cite this brief

Drug Landscape (2026). CRS-207 — Competitive Intelligence Brief. https://druglandscape.com/ci/crs-207. Accessed 2026-05-13.

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