Who are Cross-over to Osimertinib's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Osimertinib (Osi), Aumolertinib Oral Tablet, AZD9291 Dosing, Osimertinib tablet, Osimertinib Mesylate Tablets, HS-10241+ Almonertinib.

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Last reviewed 2026-05-16 · How we verify

Cross-over to Osimertinib — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cross-over to Osimertinib (Cross-over to Osimertinib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: EGFR tyrosine kinase inhibitor (third-generation). Area: Oncology.

phase 3 EGFR tyrosine kinase inhibitor (third-generation) EGFR (Epidermal Growth Factor Receptor) Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Cross-over to Osimertinib (Cross-over to Osimertinib) — AstraZeneca. Osimertinib is a third-generation EGFR tyrosine kinase inhibitor that irreversibly binds to and inhibits mutant EGFR, blocking downstream signaling in EGFR-mutant lung cancers.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Cross-over to Osimertinib TARGET	Cross-over to Osimertinib	AstraZeneca	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)
Osimertinib (Osi)	Osimertinib (Osi)	AbbVie	marketed	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)
Aumolertinib Oral Tablet	Aumolertinib Oral Tablet	Shanghai Cancer Hospital, China	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)
AZD9291 Dosing	AZD9291 Dosing	AstraZeneca	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)
Osimertinib tablet	Osimertinib tablet	Shanghai JMT-Bio Inc.	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)
Osimertinib Mesylate Tablets	Osimertinib Mesylate Tablets	Sun Yat-sen University	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (epidermal growth factor receptor), particularly mutant forms including T790M
HS-10241+ Almonertinib	HS-10241+ Almonertinib	Jiangsu Hansoh Pharmaceutical Co., Ltd.	phase 3	EGFR tyrosine kinase inhibitor (third-generation)	EGFR (Epidermal Growth Factor Receptor)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (EGFR tyrosine kinase inhibitor (third-generation) class)

AstraZeneca · 2 drugs in this class
AbbVie · 1 drug in this class
Jiangsu Hansoh Pharmaceutical Co., Ltd. · 1 drug in this class
Shanghai Cancer Hospital, China · 1 drug in this class
Shanghai JMT-Bio Inc. · 1 drug in this class
Sun Yat-sen University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cross-over to Osimertinib — Competitive Intelligence Brief. https://druglandscape.com/ci/cross-over-to-osimertinib. Accessed 2026-05-16.

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