Who are Crofelemer Powder for Oral Solution's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Brenzavvy, Jardiance, Invokana Pill, Dapagliflozin + Lobeglitazone, SGLT2i+Metformin+Cofrogliptin, Keverprazan 10 days.

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Last reviewed 2026-05-18 · How we verify

Crofelemer Powder for Oral Solution — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Crofelemer Powder for Oral Solution (Crofelemer Powder for Oral Solution) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: SGLT2 inhibitor. Area: Gastroenterology.

phase 2 SGLT2 inhibitor SGLT2 Gastroenterology Small molecule Live · refreshed every 30 min

Target snapshot

Crofelemer Powder for Oral Solution (Crofelemer Powder for Oral Solution) — Napo Therapeutics, S.p.A.. Crofelemer is a plant-derived inhibitor of the sodium glucose cotransporter 2 (SGLT2)

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Crofelemer Powder for Oral Solution TARGET	Crofelemer Powder for Oral Solution	Napo Therapeutics, S.p.A.	phase 2	SGLT2 inhibitor	SGLT2
Brenzavvy	BEXAGLIFLOZIN	Theracosbio	marketed	Sodium-Glucose Cotransporter 2 Inhibitor [EPC]	SGLT2	2023-01-01
Jardiance	empagliflozin	Boehringer Ingelheim	marketed	Sodium-Glucose Cotransporter 2 Inhibitor [EPC]	SGLT2	2014-01-01
Invokana Pill	Invokana Pill	AgelessRx	marketed	SGLT2 inhibitor	SGLT2 (sodium-glucose cotransporter 2)
Dapagliflozin + Lobeglitazone	Dapagliflozin + Lobeglitazone	Seoul National University Bundang Hospital	marketed	SGLT2 inhibitor + thiazolidinedione combination	SGLT2 and PPAR-γ
SGLT2i+Metformin+Cofrogliptin	SGLT2i+Metformin+Cofrogliptin	Huazhong University of Science and Technology	marketed	SGLT2 inhibitor + Biguanide + DPP-4 inhibitor (fixed-dose combination)	SGLT2, mitochondrial complex I, DPP-4
Keverprazan 10 days	Keverprazan 10 days	Second Affiliated Hospital, School of Medicine, Zhejiang University	marketed	SGLT2 inhibitor	SGLT2

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (SGLT2 inhibitor class)

Daewon Pharmaceutical Co., Ltd. · 13 drugs in this class
Qilu Pharmaceutical Co., Ltd. · 10 drugs in this class
Takeda · 10 drugs in this class
Taejoon Pharmaceutical Co., Ltd. · 9 drugs in this class
Hanmi Pharmaceutical Company Limited · 9 drugs in this class
Addpharma Inc. · 9 drugs in this class
GlaxoSmithKline · 7 drugs in this class
AO GENERIUM · 7 drugs in this class
Merck Sharp & Dohme LLC · 7 drugs in this class
Nobelpharma · 6 drugs in this class

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Cite this brief

Drug Landscape (2026). Crofelemer Powder for Oral Solution — Competitive Intelligence Brief. https://druglandscape.com/ci/crofelemer-powder-for-oral-solution. Accessed 2026-05-18.

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