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Xalkori — Competitive Intelligence Brief

Xalkori (crizotinib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Kinase Inhibitor [EPC]. Area: Oncology.

marketed Kinase Inhibitor [EPC] Hepatocyte growth factor receptor Oncology Live · refreshed every 30 min

Target snapshot

Xalkori (crizotinib) — Pfizer. Xalkori works by blocking the hepatocyte growth factor receptor, a protein that helps cancer cells grow and spread.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Xalkori TARGET crizotinib Pfizer marketed Kinase Inhibitor [EPC] Hepatocyte growth factor receptor 2011-01-01
Tabrecta CAPMATINIB Novartis Pharm marketed Kinase Inhibitor Hepatocyte growth factor receptor 2020-01-01
Xalkori Crizotinib Pfizer marketed Kinase Inhibitor [EPC] Hepatocyte growth factor receptor 2011-01-01
RYBREVANT AMIVANTAMAB-VMJW JANSSEN BIOTECH marketed Epidermal growth factor receptor, Hepatocyte growth factor receptor
(CARBAMIDE®) (CARBAMIDE®) German University in Cairo marketed Cyclin-dependent kinase-like 5, Hepatocyte growth factor receptor
Onartuzumab (MetMab) Onartuzumab (MetMab) Genentech, Inc. phase 3 MET inhibitor monoclonal antibody MET (hepatocyte growth factor receptor)
Wayrilz RILZABRUTINIB Genzyme Corp marketed Kinase Inhibitor [EPC] 2025-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Kinase Inhibitor [EPC] class)

  1. · 12 drugs in this class
  2. Pfizer · 7 drugs in this class
  3. Novartis · 3 drugs in this class
  4. Bayer · 2 drugs in this class
  5. Boehringer Ingelheim · 2 drugs in this class
  6. AstraZeneca · 2 drugs in this class
  7. Beigene Usa Inc · 1 drug in this class
  8. BeiGene · 1 drug in this class
  9. AbbVie · 1 drug in this class
  10. Bristol · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Xalkori — Competitive Intelligence Brief. https://druglandscape.com/ci/crizotinib. Accessed 2026-05-13.

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