Last reviewed · How we verify

crisaborole ointment — Competitive Intelligence Brief

crisaborole ointment (crisaborole ointment) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PDE4 inhibitor. Area: Dermatology.

phase 3 PDE4 inhibitor PDE4 Dermatology Small molecule Live · refreshed every 30 min

Target snapshot

crisaborole ointment (crisaborole ointment) — Pfizer. Crisaborole inhibits phosphodiesterase 4 (PDE4), leading to increased levels of cyclic AMP (cAMP) which has anti-inflammatory effects.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
crisaborole ointment TARGET crisaborole ointment Pfizer phase 3 PDE4 inhibitor PDE4
Otezla APREMILAST Amgen marketed Phosphodiesterase 4 Inhibitor [EPC] PDE4 2014-01-01
Apremilast (CC-10004) Apremilast (CC-10004) Virginia Clinical Research, Inc. marketed Phosphodiesterase 4 (PDE4) inhibitor PDE4
Crisaborole ointment, 2% Crisaborole ointment, 2% Pfizer marketed Phosphodiesterase 4 (PDE4) inhibitor PDE4
Crisaborole Vehicle Crisaborole Vehicle Pfizer marketed Phosphodiesterase 4 (PDE4) inhibitor PDE4
GSK5733584 GSK5733584 GlaxoSmithKline phase 3 PDE4 inhibitor PDE4
SPD503 (4 mg) SPD503 (4 mg) Shire phase 3 Phosphodiesterase 4 (PDE4) inhibitor PDE4

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PDE4 inhibitor class)

  1. GlaxoSmithKline · 7 drugs in this class
  2. Almirall, S.A. · 4 drugs in this class
  3. Pfizer · 3 drugs in this class
  4. Dr. Reddy's Laboratories Limited · 1 drug in this class
  5. Galderma R&D · 1 drug in this class
  6. Handok Inc. · 1 drug in this class
  7. R-Pharm · 1 drug in this class
  8. Advenchen Pharmaceuticals, LLC. · 1 drug in this class
  9. Shaanxi Micot Pharmaceutical Technology Co., Ltd. · 1 drug in this class
  10. Amgen · 1 drug in this class

Subscribe to ongoing alerts

Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:

Cite this brief

Drug Landscape (2026). crisaborole ointment — Competitive Intelligence Brief. https://druglandscape.com/ci/crisaborole-ointment. Accessed 2026-05-14.

Build your own brief

Pick any drug + add comparators: