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COV155 — Competitive Intelligence Brief
phase 3
Norepinephrine reuptake inhibitor (NRI)
Norepinephrine transporter (NET)
Neurology / Psychiatry
Small molecule
Live · refreshed every 30 min
Target snapshot
COV155 (COV155) — Mallinckrodt. COV155 is a selective norepinephrine reuptake inhibitor that increases norepinephrine levels in the central nervous system.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| COV155 TARGET | COV155 | Mallinckrodt | phase 3 | Norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| Atomoxetine (ATO) | Atomoxetine (ATO) | Janssen Research & Development, LLC | marketed | Norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| SPN-812 (600mg, QD) | SPN-812 (600mg, QD) | Supernus Pharmaceuticals, Inc. | marketed | Selective norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| Strattera (atomoxetine) | Strattera (atomoxetine) | Massachusetts General Hospital | marketed | Selective norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| atomoxetine (or placebo) | atomoxetine (or placebo) | University of Arizona | marketed | Norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| Atomoxetine (Strattera) | Atomoxetine (Strattera) | University of Pittsburgh | marketed | Norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) | |
| AXS-14 (Esreboxetine) | AXS-14 (Esreboxetine) | Axsome Therapeutics, Inc. | phase 3 | Norepinephrine reuptake inhibitor (NRI) | Norepinephrine transporter (NET) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Norepinephrine reuptake inhibitor (NRI) class)
- Axsome Therapeutics, Inc. · 2 drugs in this class
- Janssen Research & Development, LLC · 1 drug in this class
- Mallinckrodt · 1 drug in this class
- University of Arizona · 1 drug in this class
- University of Pittsburgh · 1 drug in this class
- Vrije Universiteit Brussel · 1 drug in this class
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- COV155 CI watch — RSS
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- COV155 alone — RSS
- Whole Norepinephrine reuptake inhibitor (NRI) class — RSS
Cite this brief
Drug Landscape (2026). COV155 — Competitive Intelligence Brief. https://druglandscape.com/ci/cov155. Accessed 2026-05-14.
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