Who are Comparator: niacin's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Nicotinic acid (niacin), fatty acids, omega-3, nicotinic acid/laropiprant, omega-3-fatty acids (Omegaven), Niacin Extended Release/Lovastatin, Omega-3 Supplementation.

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Last reviewed 2026-06-10 · How we verify

Comparator: niacin — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparator: niacin (Comparator: niacin) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Lipid-modifying agent; B vitamin. Area: Cardiovascular.

phase 3 Lipid-modifying agent; B vitamin GPR109A (hydroxycarboxylic acid receptor 2) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Comparator: niacin (Comparator: niacin) — Merck Sharp & Dohme LLC. Niacin (vitamin B3) raises HDL cholesterol and lowers triglycerides and LDL cholesterol by inhibiting hepatic VLDL production and increasing apolipoprotein A-I.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Comparator: niacin TARGET	Comparator: niacin	Merck Sharp & Dohme LLC	phase 3	Lipid-modifying agent; B vitamin	GPR109A (hydroxycarboxylic acid receptor 2)
Nicotinic acid (niacin)	Nicotinic acid (niacin)	Charite University, Berlin, Germany	marketed	Lipid-modifying agent; B vitamin	GPR109A (HM74A receptor)
fatty acids, omega-3	fatty acids, omega-3	National Heart, Lung, and Blood Institute (NHLBI)	marketed	Lipid-modifying agent
nicotinic acid/laropiprant	nicotinic acid/laropiprant	Manchester University NHS Foundation Trust	marketed	Lipid-modifying agent / Antilipemic	GPR109A receptor (laropiprant component); nicotinic acid acts on multiple lipid metabolism pathways
omega-3-fatty acids (Omegaven)	omega-3-fatty acids (Omegaven)	Li Shin Hospital	marketed	Lipid-modifying agent; anti-inflammatory
Niacin Extended Release/Lovastatin	Niacin Extended Release/Lovastatin	In His Image	marketed	Statin/Niacin combination; Lipid-modifying agent	HMG-CoA reductase (lovastatin); GPR109A/PUMA-G receptor (niacin)
Omega-3 Supplementation	Omega-3 Supplementation	Università degli Studi di Brescia	marketed	Dietary supplement / Lipid-modifying agent	GPR120, GPR40, PPAR-γ, NF-κB signaling pathway

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Lipid-modifying agent; B vitamin class)

Charite University, Berlin, Germany · 1 drug in this class
Merck Sharp & Dohme LLC · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Comparator: niacin — Competitive Intelligence Brief. https://druglandscape.com/ci/comparator-niacin. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing