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Comparator: lovastatin — Competitive Intelligence Brief
phase 3
Statin (HMG-CoA reductase inhibitor)
HMG-CoA reductase
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
Comparator: lovastatin (Comparator: lovastatin) — Organon and Co. Lovastatin inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, thereby reducing LDL cholesterol levels.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Comparator: lovastatin TARGET | Comparator: lovastatin | Organon and Co | phase 3 | Statin (HMG-CoA reductase inhibitor) | HMG-CoA reductase | |
| Crestor | rosuvastatin | AstraZeneca | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase | 2003-01-01 |
| Lipitor | atorvastatin | Pfizer Inc. | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase | 1996-12-17 |
| FLUVASTATIN SODIUM | FLUVASTATIN SODIUM | marketed | HMG-CoA reductase | 1993-01-01 | ||
| Lescol | FLUVASTATIN | Novartis | marketed | HMG-CoA Reductase Inhibitor | HMG-CoA reductase | 1993-01-01 |
| Continue Ritonavir-boosted PI+Rosuvastatin | Continue Ritonavir-boosted PI+Rosuvastatin | Juan A. Arnaiz | marketed | Antiretroviral combination (protease inhibitor + statin) | HIV protease (PI component); HMG-CoA reductase (rosuvastatin component) | |
| Simvastatin (Zocor) | Simvastatin (Zocor) | New York State Psychiatric Institute | marketed | HMG-CoA reductase inhibitor (statin) | HMG-CoA reductase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Statin (HMG-CoA reductase inhibitor) class)
- Organon and Co · 2 drugs in this class
- AstraZeneca · 1 drug in this class
- Mitsukoshi Health and Welfare Foundation · 1 drug in this class
- National Taiwan University Hospital · 1 drug in this class
- Shenyang Northern Hospital · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Comparator: lovastatin — Competitive Intelligence Brief. https://druglandscape.com/ci/comparator-lovastatin. Accessed 2026-06-09.
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