Who are Comirnaty Omicron XBB.1.5's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): mRNA-1273 Variant-containing Formulation, BNT162b5 Bivalent (Original/OMI BA.4/BA.5), Heterologous mRNA booster vaccine, Moderna mRNA-1273 COVID-19 vaccine, COVID-19 mRNA vaccine, bivalent BNT162b2 (original/Omi BA.4/BA.5).

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Last reviewed 2026-05-16 · How we verify

Comirnaty Omicron XBB.1.5 — Competitive Intelligence Brief

Comirnaty Omicron XBB.1.5 (Comirnaty Omicron XBB.1.5) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: mRNA vaccine. Area: Immunology / Infectious Disease.

marketed mRNA vaccine SARS-CoV-2 spike protein (XBB.1.5 variant) Immunology / Infectious Disease Biologic Live · refreshed every 30 min

Target snapshot

Comirnaty Omicron XBB.1.5 (Comirnaty Omicron XBB.1.5) — Jules Bordet Institute. Comirnaty Omicron XBB.1.5 is an mRNA vaccine that instructs cells to produce the spike protein of the XBB.1.5 Omicron variant, triggering immune recognition and antibody production against this SARS-CoV-2 strain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Comirnaty Omicron XBB.1.5 TARGET	Comirnaty Omicron XBB.1.5	Jules Bordet Institute	marketed	mRNA vaccine	SARS-CoV-2 spike protein (XBB.1.5 variant)
mRNA-1273 Variant-containing Formulation	mRNA-1273 Variant-containing Formulation	ModernaTX, Inc.	marketed	mRNA vaccine	SARS-CoV-2 spike protein (variant-specific)
BNT162b5 Bivalent (Original/OMI BA.4/BA.5)	bnt162b5-bivalent-original-omi-ba-4-ba-5	Pfizer	marketed	mRNA vaccine	Spike protein of SARS-CoV-2
Heterologous mRNA booster vaccine	Heterologous mRNA booster vaccine	Tan Tock Seng Hospital	marketed	mRNA vaccine
Moderna mRNA-1273 COVID-19 vaccine	Moderna mRNA-1273 COVID-19 vaccine	National Institute of Allergy and Infectious Diseases (NIAID)	marketed	mRNA vaccine	SARS-CoV-2 spike protein (S protein)
COVID-19 mRNA vaccine	COVID-19 mRNA vaccine	Vaccine Company, Inc.	marketed	mRNA vaccine	SARS-CoV-2 spike protein (S protein)
bivalent BNT162b2 (original/Omi BA.4/BA.5)	bivalent-bnt162b2-original-omi-ba-4-ba-5	Pfizer	marketed	mRNA vaccine	SARS-CoV-2 virus

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (mRNA vaccine class)

Pfizer · 12 drugs in this class
ModernaTX, Inc. · 11 drugs in this class
BioNTech SE · 5 drugs in this class
Jules Bordet Institute · 5 drugs in this class
Tan Tock Seng Hospital · 2 drugs in this class
Clover Biopharmaceuticals AUS Pty · 1 drug in this class
CanSino Biologics Inc. · 1 drug in this class
Assistance Publique - Hôpitaux de Paris · 1 drug in this class
CSPC Megalith Biopharmaceutical Co.,Ltd. · 1 drug in this class
Jens D Lundgren, MD · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Comirnaty Omicron XBB.1.5 — Competitive Intelligence Brief. https://druglandscape.com/ci/comirnaty-omicron-xbb-1-5. Accessed 2026-05-16.

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