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combination of irinotecan and cisplatin — Competitive Intelligence Brief
phase 3
Topoisomerase inhibitor and platinum-based chemotherapy
Topoisomerase I and DNA
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
combination of irinotecan and cisplatin (combination of irinotecan and cisplatin) — Japan Clinical Oncology Group. Irinotecan inhibits topoisomerase I, while cisplatin induces DNA crosslinks, both mechanisms leading to cell death in rapidly dividing cancer cells.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| combination of irinotecan and cisplatin TARGET | combination of irinotecan and cisplatin | Japan Clinical Oncology Group | phase 3 | Topoisomerase inhibitor and platinum-based chemotherapy | Topoisomerase I and DNA |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topoisomerase inhibitor and platinum-based chemotherapy class)
- Japan Clinical Oncology Group · 1 drug in this class
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Cite this brief
Drug Landscape (2026). combination of irinotecan and cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/combination-of-irinotecan-and-cisplatin. Accessed 2026-05-18.
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