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CNTO 148 — Competitive Intelligence Brief

CNTO 148 (CNTO 148) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: TNF-α inhibitor (monoclonal antibody). Area: Immunology.

phase 3 TNF-α inhibitor (monoclonal antibody) TNF-α (Tumor Necrosis Factor-alpha) Immunology Small molecule Live · refreshed every 30 min

Target snapshot

CNTO 148 (CNTO 148) — Janssen Pharmaceutical K.K.. CNTO 148 is a monoclonal antibody that blocks tumor necrosis factor-alpha (TNF-α), reducing inflammatory signaling in immune-mediated diseases.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CNTO 148 TARGET CNTO 148 Janssen Pharmaceutical K.K. phase 3 TNF-α inhibitor (monoclonal antibody) TNF-α (Tumor Necrosis Factor-alpha)
Infliximab and immunosuppressives Infliximab and immunosuppressives Children's Hospital of Fudan University marketed TNF-α inhibitor (monoclonal antibody) + immunosuppressive agents TNF-α receptor (via infliximab); multiple targets depending on co-administered immunosuppressive
SB5 SB5 Samsung Bioepis Co., Ltd. marketed TNF-α inhibitor (monoclonal antibody); biosimilar TNF-α (tumor necrosis factor-alpha)
Adalimumab and its biosimilars Adalimumab and its biosimilars Hanyang University Seoul Hospital marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)
Adalimumab (ADA) Adalimumab (ADA) JHSPH Center for Clinical Trials marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)
Adalimumab (Humira) Adalimumab (Humira) Tufts Medical Center marketed TNF-α inhibitor (monoclonal antibody) TNF-α (Tumor Necrosis Factor-alpha)
Infliximab biosimilar Infliximab biosimilar Hanyang University Seoul Hospital marketed TNF-α inhibitor (monoclonal antibody) TNF-α (tumor necrosis factor-alpha)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (TNF-α inhibitor (monoclonal antibody) class)

  1. Merck Sharp & Dohme LLC · 3 drugs in this class
  2. Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · 2 drugs in this class
  3. Hanyang University Seoul Hospital · 2 drugs in this class
  4. Biocad · 1 drug in this class
  5. Children's Memorial Health Institute, Poland · 1 drug in this class
  6. Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives · 1 drug in this class
  7. Centocor, Inc. · 1 drug in this class
  8. Hikma Pharmaceuticals LLC · 1 drug in this class
  9. Hospital de Manises · 1 drug in this class
  10. Celltrion · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CNTO 148 — Competitive Intelligence Brief. https://druglandscape.com/ci/cnto-148. Accessed 2026-05-13.

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