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Cladribine Pill — Competitive Intelligence Brief

Cladribine Pill (Cladribine Pill) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Purine nucleoside analog. Area: Immunology; Oncology.

phase 3 Purine nucleoside analog Ribonucleotide reductase; DNA incorporation Immunology; Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Cladribine Pill (Cladribine Pill) — Haukeland University Hospital. Cladribine is a purine nucleoside analog that inhibits ribonucleotide reductase and gets incorporated into DNA, leading to selective depletion of lymphocytes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Cladribine Pill TARGET Cladribine Pill Haukeland University Hospital phase 3 Purine nucleoside analog Ribonucleotide reductase; DNA incorporation
Gemzar Gemcitabine Hydrochloride Accord Hlthcare marketed Nucleoside metabolic inhibitor Ribonucleotide reductase; DNA incorporation 1996-01-01
Cladribine Tablets Cladribine Tablets Keith Edwards, M.D. marketed Purine nucleoside analog Ribonucleotide reductase; DNA incorporation
Gemcitabine Injectable Product Gemcitabine Injectable Product Henan Cancer Hospital marketed Nucleoside analog antimetabolite Ribonucleotide reductase; DNA incorporation
Gemcitabine monotherapy Gemcitabine monotherapy AstraZeneca phase 3 Nucleoside analog; antimetabolite Ribonucleotide reductase; DNA incorporation
Gemcitabine Hydrochloride Injection Gemcitabine Hydrochloride Injection Chia Tai Tianqing Pharmaceutical Group Co., Ltd. phase 3 Nucleoside analog; antimetabolite Ribonucleotide reductase; DNA incorporation
Cladribine (CLAD) Cladribine (CLAD) M.D. Anderson Cancer Center marketed Purine nucleoside analog DNA (via deoxyadenosine analog incorporation)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

Sponsor landscape (Purine nucleoside analog class)

  1. Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany · 2 drugs in this class
  2. Haukeland University Hospital · 1 drug in this class
  3. Keith Edwards, M.D. · 1 drug in this class
  4. M.D. Anderson Cancer Center · 1 drug in this class
  5. Nanfang Hospital, Southern Medical University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cladribine Pill — Competitive Intelligence Brief. https://druglandscape.com/ci/cladribine-pill. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing