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Last reviewed 2026-05-17 · How we verify

Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone (Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Multi-agent chemotherapy regimen. Area: Oncology.

phase 3 Multi-agent chemotherapy regimen Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone (Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone) — St. Jude Children's Research Hospital. This is a multi-drug chemotherapy regimen that combines nucleoside analogs, alkylating agents, and anthracyclines to kill rapidly dividing leukemic cells through DNA damage and inhibition of DNA synthesis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class
Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone TARGET	Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone	St. Jude Children's Research Hospital	phase 3	Multi-agent chemotherapy regimen
HDS vs ProMECE/CytaBOM	HDS vs ProMECE/CytaBOM	Gruppo Italiano Studio Linfomi	phase 3	Multi-agent chemotherapy regimen
Induction Cycles A4-5	Induction Cycles A4-5	Nationwide Children's Hospital	phase 3	Multi-agent chemotherapy regimen
Modified HIT-SKK Cycle B4-5	Modified HIT-SKK Cycle B4-5	Nationwide Children's Hospital	phase 3	Multi-agent chemotherapy regimen
PACx14	PACx14	SWOG Cancer Research Network	phase 3	Multi-agent chemotherapy regimen
A arm (CLAG-M)	A arm (CLAG-M)	Polish Adult Leukemia Group	phase 3	Multi-agent chemotherapy regimen
PAx5/PCMx5	PAx5/PCMx5	SWOG Cancer Research Network	phase 3	Multi-agent chemotherapy regimen

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Multi-agent chemotherapy regimen class)

St. Jude Children's Research Hospital · 3 drugs in this class
Nationwide Children's Hospital · 2 drugs in this class
SWOG Cancer Research Network · 2 drugs in this class
Children's Cancer Group, China · 1 drug in this class
Gruppo Italiano Studio Linfomi · 1 drug in this class
Polish Adult Leukemia Group · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Cladribine, Cyclophosphamide, Cytarabine, Daunorubicin, Dexamethasone — Competitive Intelligence Brief. https://druglandscape.com/ci/cladribine-cyclophosphamide-cytarabine-daunorubicin-dexamethasone. Accessed 2026-05-17.

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