citrate of caffeine — Competitive Intelligence Brief

citrate of caffeine (citrate of caffeine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Central nervous system stimulant. Area: Neurology.

phase 3 Central nervous system stimulant Adenosine receptor Neurology Small molecule

Target snapshot

citrate of caffeine (citrate of caffeine) — Assistance Publique Hopitaux De Marseille. Caffeine citrate acts as a central nervous system stimulant by inhibiting adenosine receptors.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
citrate of caffeine TARGET	citrate of caffeine	Assistance Publique Hopitaux De Marseille	phase 3	Central nervous system stimulant	Adenosine receptor
Nourianz	ISTRADEFYLLINE	Kyowa Kirin	marketed	CYP3A4 Substrates	Adenosine receptor A2a	2019-01-01
Singulair	montelukast	Merck & Co.	marketed	Leukotriene receptor antagonist (LTRA)	Cytochrome P450 2C8, Adenosine receptor A3, Cysteinyl leukotriene receptor 2	1998-02-20
Neurontin	gabapentin	Generic (originally Parke-Davis/Pfizer)	marketed	Gabapentinoid (anticonvulsant/neuropathic pain agent)	Large neutral amino acids transporter small subunit 1, Adenosine receptor A1, Alpha-2A adrenergic receptor	1993-12-30
Lariam	MEFLOQUINE HYDROCHLORIDE		marketed	Antimalarial	Adenosine receptor A2a	1989-01-01
Lariam	MEFLOQUINE		marketed	Antimalarial	Adenosine receptor A2a	1989-01-01
Adenocard	ADENOSINE	Astellas Pharma	marketed	Adenosine Receptor Agonist [EPC]	Adenosine receptor A3	1989-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Central nervous system stimulant class)

1. Impax Laboratories, LLC · 2 drugs in this class
2. Janssen-Cilag International NV · 2 drugs in this class
3. Alza Corporation, DE, USA · 1 drug in this class
4. Assistance Publique Hopitaux De Marseille · 1 drug in this class
5. Eli Lilly and Company · 1 drug in this class
6. McMaster University · 1 drug in this class
7. McNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc. · 1 drug in this class
8. Nanogen Pharmaceutical Biotechnology Joint Stock Company · 1 drug in this class
9. Novartis · 1 drug in this class
10. Phytopharm Consulting Brazil · 1 drug in this class