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CHS-1420 — Competitive Intelligence Brief
phase 3
Bispecific antibody
CD47 and CD40
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
CHS-1420 (CHS-1420) — Coherus Oncology, Inc.. CHS-1420 is a bispecific antibody that simultaneously engages CD47 on tumor cells and CD40 on antigen-presenting cells to enhance anti-tumor immunity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CHS-1420 TARGET | CHS-1420 | Coherus Oncology, Inc. | phase 3 | Bispecific antibody | CD47 and CD40 | |
| Elrexfio | Elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrexfio | elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrantamab | elrantamab | Pfizer | marketed | Bispecific Antibody | BCMA (B-cell maturation antigen) | |
| Mosunetuzumab (SC) | Mosunetuzumab (SC) | The Lymphoma Academic Research Organisation | phase 3 | Bispecific antibody (T-cell engager) | CD20 and CD3 | |
| AK112, Carboplatin, Paxlitaxel | AK112, Carboplatin, Paxlitaxel | Akeso | phase 3 | Bispecific antibody (PD-1/LAG-3 inhibitor) + chemotherapy combination | PD-1 and LAG-3 | |
| AK112, Gemcitabine, Cisplatin | AK112, Gemcitabine, Cisplatin | Akeso | phase 3 | Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy | PD-1 and LAG-3 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific antibody class)
- Shanghai Miracogen Inc. · 3 drugs in this class
- Atom Therapeutics Co., Ltd · 2 drugs in this class
- Pfizer · 2 drugs in this class
- Allergan · 1 drug in this class
- AstraZeneca · 1 drug in this class
- BioNTech SE · 1 drug in this class
- DualityBio Inc. · 1 drug in this class
- Coherus Oncology, Inc. · 1 drug in this class
- Genmab · 1 drug in this class
- Amgen · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- CHS-1420 CI watch — RSS
- CHS-1420 CI watch — Atom
- CHS-1420 CI watch — JSON
- CHS-1420 alone — RSS
- Whole Bispecific antibody class — RSS
Cite this brief
Drug Landscape (2026). CHS-1420 — Competitive Intelligence Brief. https://druglandscape.com/ci/chs-1420. Accessed 2026-05-14.
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