Who are Chlorthalidone plus amiloride's main competitors?

No direct comparators detected in our index.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-06-10 · How we verify

Chlorthalidone plus amiloride — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Chlorthalidone plus amiloride (Chlorthalidone plus amiloride) competitive landscape: 0 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Thiazide-like diuretic plus potassium-sparing diuretic combination. Area: Cardiovascular.

phase 3 Thiazide-like diuretic plus potassium-sparing diuretic combination Na-Cl cotransporter (chlorthalidone); epithelial sodium channel ENaC (amiloride) Cardiovascular Small molecule Live · refreshed every 30 min

Target snapshot

Chlorthalidone plus amiloride (Chlorthalidone plus amiloride) — Hospital de Clinicas de Porto Alegre. Chlorthalidone is a thiazide-like diuretic that reduces sodium reabsorption in the distal convoluted tubule, while amiloride is a potassium-sparing diuretic that blocks sodium channels in the collecting duct, together lowering blood pressure and reducing fluid overload.

Comparator set

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chlorthalidone plus amiloride TARGET	Chlorthalidone plus amiloride	Hospital de Clinicas de Porto Alegre	phase 3	Thiazide-like diuretic plus potassium-sparing diuretic combination	Na-Cl cotransporter (chlorthalidone); epithelial sodium channel ENaC (amiloride)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Thiazide-like diuretic plus potassium-sparing diuretic combination class)

Hospital de Clinicas de Porto Alegre · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Chlorthalidone plus amiloride — Competitive Intelligence Brief. https://druglandscape.com/ci/chlorthalidone-plus-amiloride. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing