Chloroquine diphosphate — Competitive Intelligence Brief

Chloroquine diphosphate (Chloroquine diphosphate) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antimalarial agent; 4-aminoquinoline. Area: Infectious Disease; Immunology.

marketed Antimalarial agent; 4-aminoquinoline Heme; Toll-like receptors (secondary immunomodulatory effects) Infectious Disease; Immunology Small molecule

Target snapshot

Chloroquine diphosphate (Chloroquine diphosphate) — University of Sao Paulo General Hospital. Chloroquine diphosphate is an antimalarial agent that accumulates in parasitic food vacuoles and inhibits heme polymerization, leading to parasite death.

Comparator set (2 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Chloroquine diphosphate TARGET	Chloroquine diphosphate	University of Sao Paulo General Hospital	marketed	Antimalarial agent; 4-aminoquinoline	Heme; Toll-like receptors (secondary immunomodulatory effects)
Chloroquine Sulfate	Chloroquine Sulfate	Washington University School of Medicine	marketed	Antimalarial agent; 4-aminoquinoline	Heme; Toll-like receptors (immunomodulatory effects)
CQ and PQ starting on Day 42	CQ and PQ starting on Day 42	Fundação de Medicina Tropical Dr. Heitor Vieira Dourado	phase 3	Antimalarial agents	Parasite heme polymerase (CQ); hypnozoite mitochondrial electron transport (PQ)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Antimalarial agent; 4-aminoquinoline class)

1. University of Sao Paulo General Hospital · 1 drug in this class
2. Washington University School of Medicine · 1 drug in this class