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CHF 5259 — Competitive Intelligence Brief
phase 2
Sodium-activated potassium channel inhibitor
KCNN4
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
CHF 5259 (CHF 5259) — Chiesi Farmaceutici S.p.A.. CHF 5259 is a small molecule drug that acts as a selective inhibitor of the sodium-activated potassium channel, KCNN4.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CHF 5259 TARGET | CHF 5259 | Chiesi Farmaceutici S.p.A. | phase 2 | Sodium-activated potassium channel inhibitor | KCNN4 | |
| TELMINUVO Tab. (80/2.5mg) | TELMINUVO Tab. (80/2.5mg) | Chong Kun Dang Pharmaceutical | phase 3 | Sodium-activated potassium channel inhibitor | KCNN4 | |
| TEV-56248 | TEV-56248 | Teva Branded Pharmaceutical Products R&D, Inc. | phase 3 | sodium-activated potassium channel inhibitor | KCNN4 | |
| VTS-K | VTS-K | Maimonides Medical Center | marketed | sodium-activated potassium channel inhibitor | Nav1.6 | |
| SHR6390 Tablets | SHR6390 Tablets | Jiangsu HengRui Medicine Co., Ltd. | phase 3 | Sodium-activated potassium channel inhibitor | Nav1.5 | |
| TAK-816 | TAK-816 | Takeda | phase 3 | Sodium-activated potassium channel inhibitor | Nav1.5 | |
| Group VTI | Group VTI | Kasr El Aini Hospital | phase 3 | sodium-activated potassium channel inhibitor | Nav1.5 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Sodium-activated potassium channel inhibitor class)
- Chiesi Farmaceutici S.p.A. · 1 drug in this class
- Chong Kun Dang Pharmaceutical · 1 drug in this class
- Jiangsu HengRui Medicine Co., Ltd. · 1 drug in this class
- Mylan Inc. · 1 drug in this class
- Pfizer · 1 drug in this class
- Syndeio Biosciences, Inc · 1 drug in this class
- Takeda · 1 drug in this class
- Teva Branded Pharmaceutical Products R&D, Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CHF 5259 — Competitive Intelligence Brief. https://druglandscape.com/ci/chf-5259. Accessed 2026-05-14.
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