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CHF 4226 pMDI — Competitive Intelligence Brief

CHF 4226 pMDI (CHF 4226 pMDI) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: LABA/LAMA combination bronchodilator. Area: Respiratory.

phase 2 LABA/LAMA combination bronchodilator Beta-2 adrenergic receptor and M3 muscarinic receptor Respiratory Small molecule Live · refreshed every 30 min

Target snapshot

CHF 4226 pMDI (CHF 4226 pMDI) — Chiesi Farmaceutici S.p.A.. CHF 4226 is an inhaled dual bronchodilator combining a long-acting beta-2 agonist and long-acting muscarinic antagonist for maintenance treatment of chronic obstructive pulmonary disease.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CHF 4226 pMDI TARGET CHF 4226 pMDI Chiesi Farmaceutici S.p.A. phase 2 LABA/LAMA combination bronchodilator Beta-2 adrenergic receptor and M3 muscarinic receptor
Indacaterol and tiotropium Indacaterol and tiotropium University of Dundee marketed LABA/LAMA combination bronchodilator Beta-2 adrenergic receptor and M3 muscarinic receptor
CHF 1535 CHF 1535 Chiesi Farmaceutici S.p.A. phase 3 LABA/LAMA combination (Long-Acting Beta-2 Agonist / Long-Acting Muscarinic Antagonist) Beta-2 adrenergic receptor and M3 muscarinic receptor
LABA/LAMA or Placebo inhalation LABA/LAMA or Placebo inhalation Shanghai Pulmonary Hospital, Shanghai, China marketed LABA/LAMA combination bronchodilator Beta-2 adrenergic receptor and muscarinic M3 receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (LABA/LAMA combination bronchodilator class)

  1. Chiesi Farmaceutici S.p.A. · 1 drug in this class
  2. Shanghai Pulmonary Hospital, Shanghai, China · 1 drug in this class
  3. University of Dundee · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CHF 4226 pMDI — Competitive Intelligence Brief. https://druglandscape.com/ci/chf-4226-pmdi. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing