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CHF 4226 pMDI — Competitive Intelligence Brief
phase 2
LABA/LAMA combination bronchodilator
Beta-2 adrenergic receptor and M3 muscarinic receptor
Respiratory
Small molecule
Live · refreshed every 30 min
Target snapshot
CHF 4226 pMDI (CHF 4226 pMDI) — Chiesi Farmaceutici S.p.A.. CHF 4226 is an inhaled dual bronchodilator combining a long-acting beta-2 agonist and long-acting muscarinic antagonist for maintenance treatment of chronic obstructive pulmonary disease.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CHF 4226 pMDI TARGET | CHF 4226 pMDI | Chiesi Farmaceutici S.p.A. | phase 2 | LABA/LAMA combination bronchodilator | Beta-2 adrenergic receptor and M3 muscarinic receptor | |
| Indacaterol and tiotropium | Indacaterol and tiotropium | University of Dundee | marketed | LABA/LAMA combination bronchodilator | Beta-2 adrenergic receptor and M3 muscarinic receptor | |
| CHF 1535 | CHF 1535 | Chiesi Farmaceutici S.p.A. | phase 3 | LABA/LAMA combination (Long-Acting Beta-2 Agonist / Long-Acting Muscarinic Antagonist) | Beta-2 adrenergic receptor and M3 muscarinic receptor | |
| LABA/LAMA or Placebo inhalation | LABA/LAMA or Placebo inhalation | Shanghai Pulmonary Hospital, Shanghai, China | marketed | LABA/LAMA combination bronchodilator | Beta-2 adrenergic receptor and muscarinic M3 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (LABA/LAMA combination bronchodilator class)
- Chiesi Farmaceutici S.p.A. · 1 drug in this class
- Shanghai Pulmonary Hospital, Shanghai, China · 1 drug in this class
- University of Dundee · 1 drug in this class
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Cite this brief
Drug Landscape (2026). CHF 4226 pMDI — Competitive Intelligence Brief. https://druglandscape.com/ci/chf-4226-pmdi. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing