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Chemotherapy,Gemcitabine based regimen — Competitive Intelligence Brief
phase 3
Nucleoside analog; antimetabolite chemotherapy
Ribonucleotide reductase; DNA polymerase
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Chemotherapy,Gemcitabine based regimen (Chemotherapy,Gemcitabine based regimen) — Eye & ENT Hospital of Fudan University. Gemcitabine is a nucleoside analog that inhibits ribonucleotide reductase and gets incorporated into DNA, causing chain termination and apoptosis in rapidly dividing cancer cells.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Chemotherapy,Gemcitabine based regimen TARGET | Chemotherapy,Gemcitabine based regimen | Eye & ENT Hospital of Fudan University | phase 3 | Nucleoside analog; antimetabolite chemotherapy | Ribonucleotide reductase; DNA polymerase | |
| Gemcitabine (GEM) | Gemcitabine (GEM) | Sun Yat-sen University | marketed | Nucleoside analog; antimetabolite | Ribonucleotide reductase; DNA polymerase | |
| Fludarabine mono | Fludarabine mono | German CLL Study Group | phase 3 | Purine analog antimetabolite | Ribonucleotide reductase; DNA polymerase | |
| Chemotherapy, gemcitabine | Chemotherapy, gemcitabine | University of Erlangen-Nürnberg Medical School | phase 3 | Nucleoside analog; antimetabolite chemotherapy | Ribonucleotide reductase; DNA polymerase | |
| Gemcitabine alone | Gemcitabine alone | Intergroupe Francophone de Cancerologie Thoracique | phase 3 | Nucleoside analog antimetabolite | Ribonucleotide reductase; DNA polymerase | |
| clofarabine, fludarabine and busulfan, CloFluBu | clofarabine, fludarabine and busulfan, CloFluBu | Vastra Gotaland Region | phase 3 | Chemotherapy combination (nucleoside analogs + alkylating agent) | DNA synthesis and repair pathways; ribonucleotide reductase; DNA polymerase | |
| Pifeltro | DORAVIRINE | Merck & Co. | marketed | Human Immunodeficiency Virus 1 Non-Nucleoside Analog Reverse Transcriptase Inhibitor [EPC] | 2018-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Nucleoside analog; antimetabolite chemotherapy class)
- Eye & ENT Hospital of Fudan University · 1 drug in this class
- University of Erlangen-Nürnberg Medical School · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Chemotherapy,Gemcitabine based regimen — Competitive Intelligence Brief. https://druglandscape.com/ci/chemotherapy-gemcitabine-based-regimen. Accessed 2026-05-14.
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