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DURVALUMAB — Competitive Intelligence Brief
marketed
Programmed Death Ligand-1 Blocker [EPC]
PD-L1
Monoclonal antibody
Live · refreshed every 30 min
Target snapshot
DURVALUMAB (DURVALUMAB). Durvalumab binds to PD-L1, blocking its interaction with PD-1 and CD80, enhancing T-cell activation and reducing tumor size.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| DURVALUMAB TARGET | DURVALUMAB | marketed | Programmed Death Ligand-1 Blocker [EPC] | PD-L1 | 2017-01-01 | |
| AVELUMAB | AVELUMAB | marketed | Programmed Death Ligand-1 Blocker [EPC] | PD-L1 | 2017-01-01 | |
| Avelumab first-line maintenance | Avelumab first-line maintenance | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | marketed | PD-L1 inhibitor | PD-L1 | |
| Avelumab (MSB0010718C) | avelumab-msb0010718c | Pfizer | marketed | Monoclonal antibody | PD-L1 | |
| Cisplatin / Carboplatin,Gemcitabine,Cindilimab | Cisplatin / Carboplatin,Gemcitabine,Cindilimab | People's Hospital of Quzhou | marketed | Combination chemotherapy with immune checkpoint inhibitor | DNA (platinum agents, gemcitabine); PD-L1 (cindilimab) | |
| PD-1 / PD-L1 monoclonal antibody | PD-1 / PD-L1 monoclonal antibody | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | marketed | PD-1/PD-L1 inhibitor | PD-1 and/or PD-L1 | |
| Adebrelimab combined with SOX regimen | Adebrelimab combined with SOX regimen | Yang Jianjun, PhD | marketed | PD-L1 inhibitor | PD-L1 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Programmed Death Ligand-1 Blocker [EPC] class)
- · 2 drugs in this class
- AstraZeneca · 1 drug in this class
- CHECKPOINT THERAPEUTICS INC · 1 drug in this class
- Checkpoint Therapeutics Inc · 1 drug in this class
- Merck KGaA · 1 drug in this class
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- DURVALUMAB CI watch — RSS
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- DURVALUMAB CI watch — JSON
- DURVALUMAB alone — RSS
- Whole Programmed Death Ligand-1 Blocker [EPC] class — RSS
Cite this brief
Drug Landscape (2026). DURVALUMAB — Competitive Intelligence Brief. https://druglandscape.com/ci/chembl-chembl3301587. Accessed 2026-06-10.
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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing