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CGB-500 Ointment with 1% tofacitinib — Competitive Intelligence Brief

CGB-500 Ointment with 1% tofacitinib (CGB-500 Ointment with 1% tofacitinib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: JAK inhibitor. Area: Immunology.

phase 2 JAK inhibitor JAK Immunology Small molecule Live · refreshed every 30 min

Target snapshot

CGB-500 Ointment with 1% tofacitinib (CGB-500 Ointment with 1% tofacitinib) — CAGE Bio Inc.. Tofacitinib is a Janus kinase (JAK) inhibitor that suppresses the activity of JAK enzymes, which play a key role in the signaling of cytokines involved in inflammation.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
CGB-500 Ointment with 1% tofacitinib TARGET CGB-500 Ointment with 1% tofacitinib CAGE Bio Inc. phase 2 JAK inhibitor JAK
Pf-07293893 pf-07293893 Pfizer marketed JAK inhibitor Janus kinase (JAK) pathway Not available
Leqselvi DEURUXOLITINIB Sun Pharm Inds Inc marketed JAK1, JAK2, TYK2 2024-01-01
Litfulo Ritlecitinib Tosylate Pfizer marketed Kinase inhibitor Janus kinase 3 (JAK3) and tyrosine kinase expressed in hepatocellular carcinoma (TEC) kinase family 2023-01-01
Cibinqo abrocitinib Pfizer marketed Janus Kinase Inhibitor [EPC] Tyrosine-protein kinase JAK1 2022-01-01
Vonjo PACRITINIB Sobi marketed Kinase Inhibitor [EPC] Tyrosine-protein kinase JAK2 2022-01-01
Cibinqo Abrocitinib Pfizer marketed Janus Kinase Inhibitor [EPC] Tyrosine-protein kinase JAK1 2022-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (JAK inhibitor class)

  1. Pfizer · 19 drugs in this class
  2. Aclaris Therapeutics, Inc. · 2 drugs in this class
  3. Beijing Friendship Hospital · 2 drugs in this class
  4. Azienda Ospedaliero, Universitaria Pisana · 1 drug in this class
  5. CAGE Bio Inc. · 1 drug in this class
  6. CTI BioPharma · 1 drug in this class
  7. Celgene · 1 drug in this class
  8. Fred Hutchinson Cancer Center · 1 drug in this class
  9. LEO Pharma · 1 drug in this class
  10. McMaster University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). CGB-500 Ointment with 1% tofacitinib — Competitive Intelligence Brief. https://druglandscape.com/ci/cgb-500-ointment-with-1-tofacitinib. Accessed 2026-05-17.

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