Last reviewed · How we verify
CG5503 IR — Competitive Intelligence Brief
phase 3
TRPV1 antagonist
TRPV1 (Transient Receptor Potential Vanilloid 1)
Pain Management
Small molecule
Live · refreshed every 30 min
Target snapshot
CG5503 IR (CG5503 IR) — Grünenthal GmbH. CG5503 is a selective inhibitor of transient receptor potential vanilloid 1 (TRPV1) that reduces pain signaling by blocking capsaicin-sensitive nociceptors.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| CG5503 IR TARGET | CG5503 IR | Grünenthal GmbH | phase 3 | TRPV1 antagonist | TRPV1 (Transient Receptor Potential Vanilloid 1) | |
| KPI-121 Ophthalmic Suspension | KPI-121 Ophthalmic Suspension | Kala Pharmaceuticals, Inc. | phase 3 | TRPV1 antagonist / Topical anti-inflammatory | TRPV1 (Transient Receptor Potential Vanilloid 1) | |
| KPS-0373, High dose | KPS-0373, High dose | Kissei Pharmaceutical Co., Ltd. | phase 3 | TRPV1 antagonist | TRPV1 | |
| TV-44749 | TV-44749 | Teva Branded Pharmaceutical Products R&D LLC | phase 3 | TRPV1 antagonist | TRPV1 (Transient Receptor Potential Vanilloid 1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (TRPV1 antagonist class)
- Allergan · 1 drug in this class
- Grünenthal GmbH · 1 drug in this class
- Kissei Pharmaceutical Co., Ltd. · 1 drug in this class
- Teva Branded Pharmaceutical Products R&D LLC · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- CG5503 IR CI watch — RSS
- CG5503 IR CI watch — Atom
- CG5503 IR CI watch — JSON
- CG5503 IR alone — RSS
- Whole TRPV1 antagonist class — RSS
Cite this brief
Drug Landscape (2026). CG5503 IR — Competitive Intelligence Brief. https://druglandscape.com/ci/cg5503-ir. Accessed 2026-05-15.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab